摘要
目的研究阵发性房颤患者冷冻消融术前单核细胞计数与高密度脂蛋白胆固醇的比值(M/H)对术后房颤复发的预测价值。方法纳入首次应用冷冻消融术完成肺静脉即刻完全隔离的阵发性房颤患者127例,根据房颤是否复发将患者分为复发组和非复发组,评估两组背景资料及M/H值与房颤术后复发的相关性。结果127例患者的平均年龄(61.51±9.74)岁,其中女性56例(44.09%),在随访12个月后,共有37例患者发生房颤复发。术前M/H(OR=1.382,95%CI:1.152-1.659,P=0.001)是阵发性房颤冷冻消融术后房颤复发的独立危险因子。当房颤冷冻消融术前M/H值大于8.59时,其对房颤术后复发预测的敏感性是67.6%,特异性是63.3%。结论术前M/H是阵发性房颤冷冻消融术后复发的独立预测因子,术前M/H值越高,其术后复发的风险越高。
Objective To study the predictive value of monocyte-to-high-density lipoprotein cholesterol ratio (M/H) for the recurrence of paroxysmal atrial fibrillation (AF) after cryoablation. Methods We enrolled 127 paroxysmal AF patients who underwent pulmonary cryoablation successfully for the first time. They were divided into recurrent group and non-recurrent group. The risk factors for the recurrence AF were evaluated. Results A total of 127 patients (age [61.51±9.74] years, female 44.09%) with symptomatic AF underwent initial cryoablation procedure. 37 patients (29.13%) had developed AF recurrence one year after cryoablation. M/H (OR= 1.382, 95%CI: 1.152-1.659, P=0.001) was an independent risk factor for recurrence of AF after cryoablation. Using a cut-off level of 8.59, the M/H predicted the recurrence of AF after cryoablation with a sensitivity of 67.6% and a specificity of 63.3%. Conclusion Elevated pre-ablation M/H ratio is associated with an increased recurrence of AF after cryoablation.
作者
李红兵
刘鹏
郭辉辉
李柏林
马鸿兰
范力宏
卫月娇
吴岳
田刚
孙超峰
黄晖
LI Hong-Bing;LIU Peng;GUO Hui-Hui;LI Bo-Lin;MA Hong-Lan;FAN Li-Hong;WEI Yue-Jiao;WU Yue;TIAN Gang;SUN Chao-Feng;HUANG Hui(Department of Cardiology,the First Affiliated Hospital of Xi'an Jiaotong University,Xi'an,710061,Shaanxi;Department of Cardiology,the general hospital of Ningxia Medical University,Yinchuan 750004,Ningxia,China)
出处
《中国分子心脏病学杂志》
CAS
2019年第4期2964-2967,共4页
Molecular Cardiology of China
基金
2015年西安交通大学第一附属医院临床研究重点项目(XJTU1AF-CRF-2015-007)
关键词
阵发性房颤
冷冻消融
单核细胞计数/高密度脂蛋白胆固醇
Paroxysmal atrial fibrillation
Cryoablation
Monocyte-to-high-density lipoprotein cholesterol ratio
