摘要
目的分析孟鲁司特钠治疗小儿哮喘临床效果、复发及不良反应。方法选择本院2015年5月—2018年5月收治的小儿哮喘患者作为研究对象,一共80例,随机分组,各组为40例,对照组给予常规治疗,观察组在常规治疗的前提下,结合白三烯受体拮抗剂孟鲁司特钠,治疗两周后比较两组患者的治疗疗效、复发情况、不良反应。结果(1)观察组治疗有效率明显高于对照组,P<0.05。(2)观察组复发率为2.50%,对照组复发率为25.00%,观察组复发率明显低于对照组,P<0.05。同时,观察组症状缓解时间和肺部症状结束时间明显比对照组更短,P<0.05。(3)观察组不良反应率明显低于对照组,P<0.05。结论孟鲁司特钠治疗小儿哮喘的疗效确切。
Objective To analyze the clinical effect,recurrence and adverse reactions of montelukast sodium in the treatment of asthma in children. Methods 80 children with asthma admitted to the hospital from May 2015 to May 2018 were randomly divided into 40 groups.The control group was given routine treatment,and the children were given inhaled corticosteroid budesonide during acute attack.On the premise of routine treatment,the observation group was treated with montelukast sodium,a leukotriene receptor antagonist.After two weeks of treatment,the curative effect, recurrence and adverse reactions of the two groups were compared.Results (1) The effective rate of the observation group was significantly higher than that of the control group (P < 0.05).(2) The recurrence rate was 2.50% in the observation group and 25.00% in the control group.The recurrence rate in the observation group was significantly lower than that in the control group (P < 0.05).Meanwhile,the relief time of symptoms and the end time of pulmonary symptoms in the observation group were significantly shorter than those in the control group (P < 0.05).(3) The adverse reaction rate of the observation group was significantly lower than that of the control group, with statistical significance (P < 0.05).Conclusion Montelukast sodium is effective in the treatment of asthma in children.It can improve the therapeutic effect and reduce the recurrence rate.At the same time,it has fewer adverse reactions and is safe and reliable.
作者
卢文强
LU Wenqiang(Department of Neonatology,Xiaogan Maternal and Child Health Hospital,Xiaogan Hubei 432000,China)
出处
《中国继续医学教育》
2019年第28期125-127,共3页
China Continuing Medical Education
关键词
孟鲁司特钠
治疗
小儿哮喘
效果
复发
不良反应
menglusitena
treatment
childhood asthma
effects
recurrent
untoward reaction
