摘要
目的观察老年患者腹腔镜手术中使用七氟烷麻醉对保护肺功能的影响。方法以2018年6月—2019年3月在该院妇科接受腹腔镜手术治疗的患者(60例)展开研究,采用随机分配的方法将其划分为研究组30例与对照组30例,对照组给予丙泊酚、瑞芬太尼静脉靶控输注麻醉,研究组给予七氟烷吸入麻醉,对比两组肺功能测定值等指标情况。结果两组麻醉前肺功能测定值、IL-1β含量T1检测时均差异无统计学意义(P>0.05)。研究组(41.02±6.19)pg/mL、(48.44±6.48)pg/mL与对照组IL-1β含量T2(46.27±7.08)pg/mL、T3(53.36±7.27)pg/mL检测时比较差异有统计学意义(P<0.05)。研究组术后8h肺功能测定值(74.3±0.4)显著比对照组低(80.2±0.5),差异有统计学意义(t=5.468,P<0.05)。研究组患者苏醒时间(13.7±5.6)短于对照组(19.5±6.3),差异有统计学意义(t=3.769,P<0.05);研究组患者拔管时间(15.8±4.4)均比对照组(20.8±4.9)短,差异有统计学意义(t=4.158,P<0.05)。结论妇科老年患者腹腔镜手术中使用七氟烷麻醉效果明显,不仅可以保护患者的肺功能,也能有效降低IL-1β含量表达,是一种值得在临床推广使用的方法。
Objective To observe the effect of sevoflurane anesthesia on the protection of lung function in laparoscopic surgery in elderly patients.Methods Patients who underwent laparoscopic surgery in our hospital from June 2018 to March 2019(60 patients)were randomly divided into study group 30 cases and control group 30 cases,the control group received propofol and remifentanil intravenous target-controlled infusion anesthesia,the study group was given sevoflurane inhalation anesthesia,and the two groups were compared with the lung function measurement values.Results There was no significant difference in the measured lung function and IL-1βcontent T1 between the two groups before anesthesia(P>0.05).The study group(41.02±6.19)pg/mL,(48.44±6.48)pg/mL had significant differences in the detection of IL-1βcontent T2(46.27±7.08)pg/mL and T3(53.36±7.27)pg/mL,the difference was statistically significant(P<0.05).The 8 h postoperative pulmonary function(74.3±0.4)was significantly lower in the study group than in the control group(80.2±0.5),and the difference was statistically significant(t=5.469,P<0.05).The recovery time of the study group(13.7±5.6)was shorter than that of the control group(19.5±6.3),and the difference was statistically significant(t=3.769,P<0.05).The extubation time of the study group(15.8±4.4)was higher than that of the control group(20.8±4.9),the difference was statistically significant(t=4.158,P<0.05).Conclusion The sevoflurane anesthesia in gynecological elderly patients is obvious,which can not only protect the lung function of patients,but also effectively reduce the expression of IL-1β.It is a method worthy of clinical application.
作者
王志强
孙贵凯
齐丛旭
腾超
乔领
梁小燕
刘瑞
白栓成
WANG Zhi-qiang;SUN Gui-kai;QI Cong-xu;TENG Chao;QIAO Ling;LIANG Xiao-yan;LIU Rui;BAI Shuan-cheng(Department of Anesthesiology,Baotou Central Hospital,Baotou,Inner Mongolia,014040 China)
出处
《世界复合医学》
2019年第9期4-6,共3页
World Journal of Complex Medicine
关键词
七氟烷
老年人
腹腔镜手术
肺功能
Sevoflurane
Elderly
Laparoscopic surgery
Pulmonary function
