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腹腔镜胆囊切除术应用舒芬太尼联合异丙酚靶控输注麻醉的临床效果观察 被引量:4

Clinical Observation of Laparoscopic Cholecystectomy with Sufentanil Combined with Propofol Target-controlled Anesthesia
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摘要 目的应用腹腔镜胆囊切除术进行治疗的患者,术中通过舒芬太尼与异丙酚联合靶控输注麻醉,对患者的麻醉情况进行分析。方法从该院在2017年5月—2018年5月收治的进行腹腔镜胆囊切除术的患者中随机抽取出100例患者,将所有患者按照随机化方法分成两组,观察组(50例)患者通过舒芬太尼与异丙酚进行联合靶控输注麻醉,对照组(50例)患者通过异丙酚与七氟醚进行静脉注射麻醉,对两组患者的麻醉指标、围拔管期的OAA/S评分进行研究。结果观察组患者的麻醉指标分别为:呼吸正常时间(7.56±1.49)min,清醒时间(8.35±1.65)min,拔管时间(13.46±5.84)min,定向力正常时间(19.06±6.45)min,显著优良于对照组,差异有统计学意义(t=5.482 7、5.632 8、5.872 1、5.489 2,P<0.05);观察组患者围拔管期的OAA/S评分分别为:拔管1 h(4.40±1.35)分,拔管2 h(4.51±1.24)分,拔管6 h(4.80±1.31)分,拔管8 h(4.83±1.28)分,明显高于对照组患者,差异有统计学意义(t=6.431 8、6.482 7、6.438 5、6.751 9,P<0.05)。结论进行腹腔镜胆囊切除术的患者术中可以利用舒芬太尼与异丙酚通过靶控输注进行麻醉,可以取得良好的麻醉效果。 Objective To evaluate the anesthesia of patients undergoing laparoscopic cholecystectomy by intraoperative anesthesia with sufentanil and propofol combined with target-controlled infusion. Methods The authors randomly se-lected 100 patients from our hospital who underwent laparoscopic cholecystectomy from May 2017 to May 2018. All patients were randomized into two groups, the observation group (50 cases) patients underwent combined target-con-trolled infusion anesthesia with sufentanil and propofol, and patients in the control group (50 cases) underwent intra-venous anesthesia with propofol and sevoflurane. OAA/S scores and adverse reactions were studied. Results The anes-thesia indexes of the observation group were: normal breathing time(7.56±1.49)min, waking time(8.35±1.65)min, extuba-tion time(13.46±5.84)min, orientation normal time(19.06±6.45)min, significantly better than the control group, the dif-ference was statistically significant (t=5.482 7, 5.632 8, 5.872 1, 5.489 2,P<0.05);patients in the observation group of OAA/S scores were as follows: extubation 1 h(4.40±1.35)points, extubation 2 h(4.51±1.24)points, extubation 6 h(4.80± 1.31)points, extubation 8 h (4.83±1.28)points, significantly higher in the control group, the difference was statistically significant (t=6.431 8, 6.482 7, 6.438 5, 6.751 9,P<0.05). Conclusion Patients undergoing laparoscopic cholecystecto my can be anesthetized with target-controlled infusion of sufentanil and propofol during surgery. Good anesthesia can be achieved.
作者 李军 LI Jun(Department of Anesthesiology, Central Hospital of Jiangjin District, Chongqing, 402260 China)
出处 《系统医学》 2019年第17期106-108,共3页 Systems Medicine
关键词 腹腔镜胆囊切除术 舒芬太尼 异丙酚 靶控输注 Laparoscopic cholecystectomy Sufentanil Propofol Target-controlled infusion
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