摘要
研究显示,骨髓间充质干细胞(bone marrow mesenchymal stem cells, BMSCs)移植具有恢复缺血性卒中患者机体感觉和运动功能的治疗效果。BMSCs移植是一种很有前景的治疗策略,因为其具有分化为神经元样细胞的能力。文章对在体外促进BMSCs向神经元样细胞分化的诱导剂进行了综述。
Studies have shown that bone marrow mesenchymal stem cells (BMSCs) transplantation can restore the sensory and motor function of patients with ischemic stroke. BMSCs transplantation is a promising therapeutic strategy because of its ability to differentiate into neuron-like cells. This article reviews the inducers that promote BMSCs to differentiate into neuron-like cells in vitro.
作者
伦志刚
汤加家
邹昌盛
黄璟
李爱民
Lun Zhigang;Tang Jiajia;Zou Changsheng;Huang Jing;Li Aimin(Department of Neurosurgery,Lianyungang Hospital Affiliated to Xuzhou Medical University,Lianyungang 222002,China)
出处
《国际脑血管病杂志》
2019年第7期543-548,共6页
International Journal of Cerebrovascular Diseases
基金
江苏省科技计划项目(BE2015657)
连云港市第一人民医院青年英才基金项目(QN1702).
关键词
卒中
脑缺血
骨髓细胞
间质干细胞
神经元
细胞分化
Stroke
Brain ischemia
Bone marrow cells
Mesenchymal stem cells
Neurons
Cell differentiation
