摘要
目的探讨无症状性颈内动脉中重度狭窄患者发生进展性运动功能缺损(PMD)的危险因素。方法选取2017年6月至2017年12月入住海口市人民医院神经内科的无症状性颈内动脉中重度狭窄60例患者作为研究对象,根据有无发生PMD的结果分为两组,记录各组患者的临床资料。结果PMD组和非PMD组在高血压、梗死部位、病变血管、颈动脉粥样硬化不稳定斑块等方面比较,差异有统计学意义(P<0.05)。多因素Logistic回归分析显示放射冠区梗死部位、大脑中动脉中重度狭窄及颈动脉粥样硬化不稳定斑块是无症状性颈内动脉中重度狭窄患者发生PMD的高危因素(P<0.05)。结论放射冠区梗死部位、大脑中动脉中重度狭窄及颈动脉粥样硬化不稳定斑块是无症状性颈内动脉中重度狭窄患者发生PMD的独立危险因素。
Objective To investigate the risk factors of progressive motor deficit(PMD)in patients with asymptomatic moderate to severe internal carotid artery stenosis.Method Patients with asymptomatic moderate to severe internal carotid artery stenosis were admitted to the department of neurology in Haikou People’s Hospital from June 2017 to December 2017 were selected as subjects.According to whether PMD occurs or not,they are divided into two groups.The clinical data of each group were recorded.Results The PMD group and the non-PMD group had significant differences in hypertension,radiation infarction site,pathological vessel and carotid atherosclerotic plaque(P<0.05).Multivariate Logistic regression analysis showed that radiation coronal infarction site,moderate to severe stenosis of middle cerebral artery and unstable carotid atherosclerotic plaque were the risk factors for PMD in patients with asymptomatic moderate to severe internal carotid artery stenosis(P<0.05).Conclusion radiation coronal infarction site,moderate to severe stenosis of middle cerebral artery and unstable carotid atherosclerotic plaque are independent risk factors for PMD in patients with asymptomatic moderate to severe internal carotid artery stenosis.
作者
肖成业
杨国帅
余丹
程启慧
孙荣道
Xiao Chengye;Yang Guoshuai;Yu Dan;Cheng Qihui;Sun Rongdao(Department of Neurology,the People’s Hospital of Haikou,Hainan 570208,China)
出处
《脑与神经疾病杂志》
2019年第9期534-537,共4页
Journal of Brain and Nervous Diseases
基金
海南省自然科学基金(20158272)
海口市重点科技计划(2014-073)
关键词
无症状性颈内动脉中重度狭窄
进展性运动功能缺损
危险因素
Asymptomatic moderate to severe internal carotid artery stenosis
Progresssive motor deficit
Risk factors
