摘要
目的探讨赣南地区RetcamⅢ筛查早产儿视网膜病变(ROP)发生情况。方法回顾性分析2018年1月—12月在本院NICU住院行眼底筛查的396例早产患儿临床资料,均行RetcamⅢ筛查。统计ROP检出情况,并分析ROP患儿与非ROP患儿出生孕周、出生体质量、氧气和呼吸机使用情况,分析新生儿呼吸窘迫综合征、新生儿高胆红素血症、新生儿低蛋白血症、新生儿贫血、先天性支气管肺发育不良、肺炎与ROP发病关系。结果396例早产儿经RetcamⅢ筛查,检出ROP患儿57例(14.39%,100眼);ROP组≤28周、28~32周比例高于非ROP组,≥32周比例低于非ROP组,差异有统计学意义(P<0.05);ROP组<1500g高于非ROP组,1500~2500g、≥2500g低于非ROP组,差异有统计学意义(P<0.05);ROP组氧气、呼吸机使用高于非ROP组,差异有统计学意义(P<0.05);ROP组新生儿呼吸窘迫综合征、新生儿低蛋白血症、新生儿贫血、先天性支气管肺发育不良高于非ROP组,差异有统计学意义(P<0.05);两组新生儿高胆红素血症、肺炎比例对比,差异无统计学意义(P>0.05)。结论早产儿ROP患病与出生体质量、孕周、是否使用氧气和呼吸机密切相关,新生儿呼吸窘迫综合征、新生儿低蛋白血症、新生儿贫血、先天性支气管肺发育不良是ROP发生高危因素,早期行RetcamⅢ筛查可尽早发现早产儿眼部异常,及时给予合理的治疗,以减少儿童低视力与致盲率。
Objective To investigate the detection of retinopathy of prematurity(ROP) with RetcamⅢ in Southern Jiangxi.Methods The clinical data of 396 premature children hospitalized in NICU in our hospital from January to December 2018 were analyzed retrospectively.All of them were screened by RetcamⅢ.The detection of ROP was counted,and the gestational age,birth weight,oxygen and ventilator use,neonatal respiratory distress syndrome,neonatal hypercholinemia and neonatal hypoalbuminemia in ROP and non-ROP children were analyzed.Neonatal anemia,congenital bronchopnea,pneumonia and the relationship between the incidence of ROP were analyzed.Results 96 premature infants were screened by RetcamⅢ,57 cases with ROP were detected(14.39%,100 eyes);The proportion of ≤28 W,28-32 W in ROP group was higher than non-ROP group,the proportion of ≥32 W was lower than non-ROP group(P<0.05).The proportion of <1 500 g in ROP group was higher than that in non-ROP group,the proportion of 1 500-2 500 g,≥2 500 g in ROP group is lower than non-ROP group(P<0.05).The proportion of oxygen and ventilator use in ROP group was higher than that in non-ROP group(P<0.05).Neonatal respiratory distress syndrome,neonatal hypoproteinemia,neonatal anemia,and congenital bronchopulmonary dysplasia in the ROP group were higher than those in the non-ROP group(P<0.05).There was no significant difference in the proportion of neonatal hyperbilirubinemia and pneumonia between the two groups(P>0.05).Conclusion The prevalence of ROP in premature infants is closely related to birth weight,gestational age,use of oxygen and ventilator.Neonatal respiratory distress syndrome,neonatal hypoproteinemia,neonatal anemia,congenital bronchopulmonary dysplasia are the risk factors of ROP.Early RetcamⅢ screening can detect ocular abnormalities in premature infants as soon as possible and give reasonable treatment in time in order to reduce the low visual acuity and blindness rate of children.
作者
欧阳敏
OUYANG Min(Department of Ophthalmology,Ganzhou Maternal and Child Health Hospital,Ganzhou 341000,China)
出处
《国外医学（医学地理分册）》
CAS
2019年第3期213-215,共3页
Foreign Medical Sciences：Section of Medgeography
基金
赣州市卫生和计划生育委员会科研计划资助项目(No.2018-2-12)
