摘要
目的探讨中西医结合治疗法对慢性附睾炎不育症患者精液常规参数、精子形态、精浆中性α-葡糖苷含量的影响。方法将2016年6月~2018年6月就诊于某院的76例慢性附睾炎不育症患者随机分为观察组和对照组,每组各38例。对照组口服左氧氟沙星,观察组在对照组的基础上口服散结子痈汤,90 d后观察精液常规、精子形态和精浆中性α-葡糖苷含量变化情况。结果观察组总有效率(83.78%)显著高于对照组(55.56%),差异具有统计学意义(P<0.05);与治疗前比较,两组精子浓度、精子活率、前向运动精子、精浆中性糖苷酶和精子正常形态率均明显提高(P<0.01),且观察组优于对照组(P<0.01)。结论中西医结合法具有改善慢性附睾炎不育症的精液常规、精子形态及精浆中性α-葡糖苷含量的作用。
OBJECTIVE To investigate the effect of traditional Chinese combined with western medicine in the treatment of patients with chronic epididymitis infertility. METHODS A total of 76 cases with chronic epididymitis infertility were randomly divided into observation group and control group,with 38 cases each. The control group was given oral levofloxacin. Observation group treated with Sanjiezi carbuncle decoction and levofloxacin.After 90 days,the change of semen routine parameters,sperm morphology and plasma neutral alpha-glucosidase were observed. RESULTS The total effective rate of the observation group was higher than that of the control group( 83.78% vs 55.56,P<0.05).Compared with before treatment: sperm concentration,motile sperm,progressively motile sperm,plasma neutral alpha-glucosidase and percentage of morphologically normal sperm were significantly improved( P < 0. 01),with more significantly in observation group( P<0.01). CONCLUSION Integrated traditional Chinese and western medicine can improve the semen routine,sperm morphology and content of alpha-glucaglycoside in sperm plasma of chronic epididymitis infertility.
作者
郑建华
丘远聪
陈文滨
林晓敏
谢丽云
ZHENG Jianhua;QIU Yuancong;CHEN Wenbin;LIN Xiaomin;XIE Liyun(Huizhou First Hospital,Huizhou,Guangdong 516003,China)
出处
《今日药学》
CAS
2019年第8期542-545,共4页
Pharmacy Today
基金
惠州市科技项目计划(2018Y064)
关键词
慢性附睾炎不育症
精液常规
精子形态
精浆中性α-葡糖苷
chronic epididymitis infertility
semen routine
sperm morphology
plasma neutral alpha glucoside