摘要
目的探究中药治疗围绝经期综合征的临床用药特点。方法以中国知网作为数据来源,采用"中药+围绝经期"为主题进行高级检索,对近8年的检索结果进行筛选分类,筛选出关于中药复方或中成药制剂治疗围绝经期及其并发症的文献,将其录入Excel表数据库中,使用SPSS Statistics 23.0、SPSS Clementine 12.0统计软件进行数据分析。结果在纳入的134首方剂中,共涉及207种中药,使用频数≥30的药物共15种,其中以熟地黄(77次,11.53%)、山药(59次,8.83%)、白芍(55次,8.23%)等最为常见;经统计,中药治疗围绝经期综合征在用药类别上以采用补虚药(817次,47.83%)、活血化瘀药(94次,5.50%)、清热药(152次,8.90%)居多;在药性的研究中以四气“温(76次,36.71%)、寒(65次,31.40%)”药;五味“甘(106次,31.27%)、苦(89次,26.25%)”为主;归经中归肝经(115次,21.70%)的药物较多,相继是肾经(84次,15.85%)、脾经(73次,13.77%)等,共涉及12经。关联规则分析中发现潜在药对组合15种,因子分析中发现公因子6个。结论数据分析显示中药治疗围绝经期综合征多选择补虚药,活血化瘀药,清热药等,以利水渗湿药,安神药等为辅助,并着重选择药性为甘、苦;偏寒、温;归肝、肾经等药物进行配伍使用。
Objective To explore the characteristics of traditional Chinese medicine in the treatment of perimenopausal syndrome.Methods Taking China HowNet as the data source and using the theme of"Traditional Chinese Medicine+Perimenopause"for advanced retrieval,this paper screens and classifies the retrieval results in the past eight years,screens out the literature about the treatment of perimenopause and its complications by Chinese traditional medicine compound or Chinese patent medicine preparation,and puts it into Excel table database,and uses SPSS Statistics 23.0.SPSS Clementine 12.0 statistical software for data analysis.Results Among 134 prescriptions,207 kinds of Chinese medicines were involved,and 15 kinds of medicines were used more than 30 times.Among them,cooked Rehmannia glutinosa(77 times,11.53%),yam(59 times,8.83%)and Paeonia lactiflora(55 times,8.23%)were the most common.According to statistics,most of the drugs used in treating perimenopausal syndrome were tonifying deficiency drugs(46 kinds,817 times,47.83%),promoting blood circulation and removing blood stasis drugs(20 kinds,94 times,5.50%)and clearing heat drugs(20 kinds,152 times,8.90%).In the study of medicinal properties,SiQi are mainly warm(76 kinds,36.71%)and cold(65 kinds,31.40%).The five flavors are mainly sweet(106 kinds,31.27%)and bitter(89 kinds,26.25%).There are more drugs in the liver meridian(115,21.70%)of the meridians,including the kidney meridian(84,15.85%)and the spleen meridian(73,13.77%)and so on,involving 12 meridians.Conclusion Data analysis showed that Chinese medicine for perimenopausal syndrome mostly chose tonic deficiency drugs,blood-activating and stasis-removing drugs,heat-clearing drugs and so on,supplemented by diuresis and dampness-relieving drugs and tranquilizing psychotropic drugs,focusing on the choice of drugs for sweet and bitter,cold and warm,liver and kidney meridians.
作者
刘田园
白明
刘保松
乔靖怡
刘会丽
苗明三
LIU Tian-yuan;BAI Ming;LIU Bao-song;QIAO Jing-yi;LIU Hui-li;MIAO Ming-san(Henan University of Chinese Medicine,Zhengzhou,450046,China)
出处
《时珍国医国药》
CAS
CSCD
北大核心
2019年第8期2018-2021,共4页
Lishizhen Medicine and Materia Medica Research
基金
河南省中原学者项目(162101510003)
国家自然科学基金(81274154)
河南省科技发展计划(162102310181)
河南省高等学校重点科研项目(15A360026)
关键词
中药
围绝经期综合征
用药规律
数据分析
Chinese medicine
Perimenopausal syndrome
Medication rule
Dataanalysis
