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吉兰-巴雷综合征患者中性粒细胞-淋巴细胞比率、血清白蛋白分析

Analysis of the Neutrophil-lymphocyte Ratio and Serum Albumin Level in Guillain-Barré Syndrome
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摘要 目的:分析吉兰-巴雷综合征(Guillain-Barrésyndrome,GBS)患者中性粒细胞-淋巴细胞比率(neutrophil-lymphocyte ratio,NLR)、血清白蛋白与病情严重程度的关系。方法:回顾性分析2016年01月至2018年12月于蚌埠医学院第一附属医院就诊的GBS患者96例,根据患者入院修斯功能分级量表(Hughes Functional Grading Scale,HFGS)评分分为两组,轻型组(HFGS≤3分)和重型组(HFGS>3分),比较两组间基本临床资料、NLR、血清白蛋白有无差异,对96例GBS患者NLR、血清白蛋白与入院HFGS评分进行相关性分析,采用GraphPad Prism 6软件进行统计分析并作图。结果:两组间年龄、NLR、血清白蛋白差异有统计学意义(P<0.05),NLR与入院HFGS评分呈正相关,血清白蛋白与入院HFGS评分呈负相关。结论:年龄、NLR、血清白蛋白可能与GBS的严重程度有关。 Objective:To analyze the relationship between neutrophil-lymphocyte ratio(NLR), serum albumin level and severity of disease in patients with Guillain-Barré syndrome(GBS). Methods:96 patients with GBS, admitted to The first affiliated hospital of Bengbu Medical College from January 2016 to December 2018, were analyzed retrospectively.They were divided into the milder group(HFGS ≤3) and the worse group(HFGS > 3) according to Hughes Functional Grading Scale(HFGS) on admission.The basic clinical data, NLR and serum albumin level were compared between the two groups. The correlation between NLR, serum albumin and HFGS on admission was analyzed in 96 patients with GBS. Statistical analysis and mapping were performed using GraphPad Prism 6 software. Results:There was significant difference in age(P<0.05), NLR(P<0.05), and serum albumin(P<0.05) between the two groups. There was positive correlation between the NLR and HFGS on admission and there was negative correlation between the serum albumin level and HFGS on admission. Conclusion:Age, NLR, and serum albumin might be related to severity of GBS.
作者 陈从艳 屈洪党 CHEN Congyan;QU Hongdang(The First affiliated Hospital of Bengbu Medical College,Bengbu 233000,China)
出处 《包头医学院学报》 CAS 2019年第7期9-11,共3页 Journal of Baotou Medical College
基金 蚌埠医学院研究生科研创新计划项目(Byycx1846)
关键词 吉兰-巴雷综合征 中性粒细胞-淋巴细胞比率 血清白蛋白 Guillain-Barré syndrome Neutrophil-lymphocyte ratio Serum albumin level
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