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基于“元精-元气论”阐释填精养脏法与干细胞移植修复组织损伤的理论同一性 被引量:13

Alignment between essence-replenishing viscera-nourishing method and modern stem cell transplantation in repairing tissue damage based on “primordial essence-qi theory”
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摘要 干细胞具有元精属性,是元精在机体微观层面的存在形式。从胚胎发生学上看,干细胞基本符合元精所有功能特征,元精化生元气,元精体现物质结构,元气体现代谢和能量传递功能,干细胞的增殖分化及成熟后能量代谢过程即为五行(即5种能量的形式)生克制化理论下元精化生元气的过程。西医利用干细胞功能特点进行组织损伤修复的技术尝试,与中医“元精-元气论”及填精养脏治法在理论上具备同一性。肾藏五脏六腑之精,干细胞直接补充先天肾精,肾精充盛,则五脏六腑之精充盈,脏腑得以濡润而恢复阴阳和合状态,促使受损组织修复,起到任何药力所不能达的效果,可谓是中医“慢病治其本”的经典范式,为中西医结合干细胞修复组织损伤的技术革新与拓展尝试提供新的思路和方法。 With the property of essence, stem cell is the existing form of essence at the micro-level of the body. From the viewpoint of embryogenesis, stem cells conform to all the functional characteristics of essence. Essence generates primordial qi and can reflect the material structure, while primordial qi can embody the function of metabolism and energy transfer. Besides, the procedure of proliferation, differentiation and energy metabolism of stem cells after maturation is similar to the process of how essence generates primordial qi, as the generating and restraining relations described in the theory of five elements(i.e. five forms of energy). Modern medicine attempts to repair tissue damage by taking advantage of the functional characteristics of stem cells, which is theoretically identical to the theory of "primordial essence-qi" in traditional Chinese medicine and the method of "tonifying essence to nourish viscera". As the kidney stores the essence, stem cells directly supplement congenital kidney essence to promote the repair of damaged tissues, playing an effect beyond the reach of any drug. It is a classic paradigm of "treating the root of chronic disease" in traditional Chinese medicine and provides new ideas and methods for the innovation and expansion of stem cell technology under the guidance of integrated theory of traditional Chinese and Western medicine.
作者 李红梅 吴芬芳 徐安龙 Li Hongmei;Wu Fenfang;Xu Anlong(School of Life Sciences,Beijing University of Chinese Medicine,Beijing 102488,China;College of Life Sciences,Sun Yat-Sen University,Guangdong 510006,China)
出处 《北京中医药大学学报》 CAS CSCD 北大核心 2019年第7期536-540,共5页 Journal of Beijing University of Traditional Chinese Medicine
关键词 元精 元气 填精养脏 干细胞 组织修复 理论同一 essence and primordial qi tonifying essence to nourish viscera stem cells tissue repair theoretical identity
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