摘要
目的研究老年患者前循环血管(颈内动脉、颅内段、大脑中动脉)狭窄程度与腔隙性脑梗死发生的相关性。方法选取2017年4月至2018年12月西安医学院第二附属医院收治的颅内动脉粥样硬化、缺血性脑梗死、短暂性脑缺血发病患者235例作为研究对象,所有患者均行MRI与CT扫描,分析患者前循环血管狭窄程度,记录所有患者腔隙性脑梗死的发生情况,采用Kendall、Spearman等级相关系数分析前循环血管狭窄与患者腔隙性脑梗死的相关性。结果 235例患者中共监测出前循环血管狭窄者202例,其中174例判定为腔隙性脑梗死,余28例未被判定腔隙性脑梗死,另外33例患者未检出前循环血管狭窄,但有2例患者检测出腔隙性脑梗死;有腔隙性脑梗死与无腔隙性脑梗死患者前循环血管狭窄情况比较差异具有统计学意义(P<0.05);Kendall相关系数、Spearman相关系数显示狭窄分级与腔隙性脑梗死之间呈负相关关系(r=-0.245,-0.265,P<0.05);多元Logistic回归分析结果显示,单侧狭窄、狭窄分级为Ⅰ级是导致腔隙性脑梗死发生的独立危险因素(P<0.05)。结论老年患者的前循环血管狭窄程度与腔隙性脑梗死发生具有相关性。
Objective To investigate the relationship between stenosis of anterior circulation vessels (internal carotid artery, intracranial segment, middle cerebral artery) and lacunar infarction in elderly patients. Methods From April 2017 to December 2018, 235 patients with intracranial atherosclerosis, ischemic cerebral infarction and transient cerebral ischemia who admitted to the Second Affiliated Hospital of Xi'an Medical College were enrolled in the study. All patients were scanned with MRI and CT. The degree of anterior circulation stenosis was analyzed, and the incidence of lacunar infarction in all patients was observed and recorded, and the correlation between anterior circulation stenosis and lacunar infarction was analyzed. Results A total of 202 cases of anterior circulation vascular stenosis were monitored in 235 patients, of which 174 cases were diagnosed as lacunar infarction, 28 cases were not diagnosed as lacunar infarction, 33 cases were not detected as anterior circulation vascular stenosis, but 2 cases were detected as lacunar infarction. There was significant difference in the situation of anterior circulation vascular stenosis between the patients with lacunar infarction and without lacunar infarction (P<0.05). Kendall correlation coefficient and Spearman correlation coefficient showed a negative correlation between stenosis classification and lacunar infarction (r=-0.245,-0.265, P<0.05). Multivariate logistic regression analysis showed that unilateral stenosis and stenosis grade Ⅰ were independent risk factors for lacunar infarction (P<0.05). Conclusion The degree of anterior circulation stenosis was correlated with lacunar infarction in elderly patients.
作者
刘利宁
惠晶
张丽辉
李毓新
LIU Li-ning;HUI Jing;ZHANG Li-hui;LI Yu-xin(Department of Neurology,the Second Affiliated Hospital of Xi'an Medical College,Xi'an 710038,Shaanxi,CHINA)
出处
《海南医学》
CAS
2019年第17期2206-2208,共3页
Hainan Medical Journal
基金
西安医学院校级科研项目(编号:12FZ06)
关键词
老年患者
前循环血管狭窄
程度
腔隙性脑梗死
相关性
Elderly patients
Anterior circulation stenosis
Severity
Lacunar infarction
Correlation
