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腹腔镜手术后特殊类型子宫肌瘤复发的相关因素及病理分析 被引量:23

Related factors with relapse in patients with special types of uterine fibroids after laparoscopic surgery
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摘要 目的探讨腹腔镜手术后特殊类型子宫肌瘤复发的相关因素及其病理特点。方法特殊类型子宫肌瘤患者64例经病理检测验证并且完成腹腔镜手术,在术后对所有患者进行术后随访,对患者的年龄、病程、肌瘤大小、肌瘤数目、肌瘤部位和既往妊娠史、分娩史进行详细记录,得出上述影响因素与患者复发率的关系。结果64例患者中有23例子宫肌瘤复发,各诊断类型患者的术前资料无差异(P>0.05);单因素分析发现患者复发率与肌瘤数目、肌瘤直径、既往分娩史明显相关(P<0.05)。多因素分析发现复发率与患者的既往分娩史和复发率呈负相关(P<0.05),肌瘤数目、肌瘤直径和复发率呈正相关(P<0.05);23例复发患者中,病理类型为富细胞型平滑肌瘤的有21例,上皮样平滑肌瘤的有2例。结论 腹腔镜手术后特殊类型子宫肌瘤行腹腔镜术后复发的主要危险因素包括三点,分别是肌瘤多发、肌瘤直径≥6cm和既往分娩史;病理分析得出复发患者中富细胞型平滑肌瘤最为多见,对于这类疾病临床中应当以控制危险因素来降低复发率。 Objective To investigate the related factors with relapse in patients with special types of uterine fibroids after laparoscopic surgery,and to explore its pathological characteristics.Methods A total of 64 patients with special types of uterine fibroids who were diagnosed pathologically and underwent laparoscopic operation in our hospital from December 2015 to December 2017 were enrolled in the study,who were followedup after surgery.The patient’s age,disease duration, myoma size, myoma location,the history of pregnancy and childbirth were record,and the correlation between above influencing factors and relapse rate of patients was analyzed.Results Among the 64 patients, 23 patients had relapse of uterine fibroids,there were no significant differences in preoperative data among the patients with different types of uterine fibroids(P>0.05). The single factor analysis showed that the relapse rate was correlated with the patient’s previous delivery history,the number of fibroids,the diameter of fibroids(P<0.05).The multiple factor analysis showed that the relapse rate was negatively correlated with the patient’s previous delivery history(P<0.05),however, the relapse rate was positively correlated with the number of fibroids and diameter of fibroids(P<0.05).Among the 23 patients with relapse,there were 21 cases of cell-rich leiomyoma and 2 cases of epithelial leiomyoma.Conclusion The main risk factors for relapse of special types of uterine fibroids after laparoscopic surgery include three points: multiple fibroids,fibroid diameter≥6 cm and previous labor history.Histopathological analysis suggests that the most common type of recurrence is the cell-rich leiomyoma,it is necessary to control the risk factors to reduce the relapse rate.
作者 孙莉 杨波 杨红玉 梁磊 闫茗诺怡 SUN Li;YANG Bo;YANG Hongyu(Department of Obstetrics and Gynecology,No.980 Hospital of PLA,Hebei,Shijiazhuang 050081,China)
出处 《河北医药》 CAS 2019年第18期2805-2808,共4页 Hebei Medical Journal
基金 河北省医学科学研究重点课题(编号:20160005)
关键词 腹腔镜 子宫肌瘤 特殊类型 相关因素 病理特点 laparoscope uterine fibroids special type related factors pathological characteristics
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