摘要
目的探讨经皮椎体成形术(PVP)联合放疗治疗椎体转移癌的临床疗效。方法选取2015年1月至2018年1月该院诊治的椎体转移癌患者60例作为研究对象,根据治疗方案分为研究组和对照组,每组各30例。研究组采用PVP联合放疗治疗,对照组采用单纯放疗治疗;采用疼痛视觉模拟评分(VAS)和美国东部肿瘤协作组(ECOG)体力状态评分表对2组患者进行评价。结果2组患者治疗后VAS评分均较治疗前降低,差异有统计学意义(P<0.05),且研究组改善情况优于对照组,差异有统计学意义(P<0.05)。研究组患者行为状态改善率为93.3%,高于对照组的70.0%,差异有统计学意义(P<0.05)。治疗期间,2组均未出现严重不良反应和并发症。结论PVP联合放疗治疗椎体转移癌能更好地缓解患者疼痛,维持椎体稳定性,改善患者生活质量。
ObjectiveTo investigate the clinical efficacy of percutaneous vertebroplasty(PVP)combined with radiotherapy for vertebral metastases.MethodsSixty patients with vertebral metastases who were diagnosed and treated in this hospital from January 2015 to January 2018 were selected as subjects.According to the treatment plan,the study group and the control group were divided into 30 groups in each group.The study group was treated with PVP combined with radiotherapy,and the control group was treated with radiotherapy alone.Two groups of patients were evaluated using the Pain Visual Analog Scale(VAS)and the Eastern Cancer Cooperative Group(ECOG)Physical Status Scale.ResultsThe VAS scores of the two groups were lower than those before treatment,and the difference was statistically significant(P<0.05).The improvement of the study group was better than that of the control group,and the difference was statistically significant(P<0.05).The improvement rate of behavioral status of the study group was 93.3%,which was higher than that of the control group(70.0%).The difference was statistically significant(P<0.05).No serious adverse reactions and complications occurred in either group during the treatment period.ConclusionPVP combined with radiotherapy for vertebral metastases can better relieve pain,maintain vertebral stability,and improve patients′quality of life.
作者
杨怡
刘佰易
YANG Yi;LIU Baiyi(Department of Cancer Center,Army Medical Center of PLA,Chongqing 400042,China;Department of Spinal Surgery,Army Medical Center of PLA,Chongqing 400042,China)
出处
《现代医药卫生》
2019年第17期2608-2610,共3页
Journal of Modern Medicine & Health
基金
国家卫生健康委员会医药卫生科技发展研究中心研究项目（W2013ZT172）
关键词
经皮椎体成形术
放疗
椎体转移癌
疼痛
行为状态
Percutaneous vertebroplasty
Radiotherapy
Vertebral metastases
Pain
Behavioral state
