摘要
目的探讨内镜直视下球囊扩张在食管癌放疗后狭窄中的临床应用。方法选取2016年1月~2019年1月我院收治的46例食管癌放疗患者,随机分为两组,对照组行探条扩张治疗,研究组行内镜直视下球囊扩张治疗。比较两组患者扩张次数、治疗效果、手术结果、炎性因子水平和并发症发生率。结果研究组与对照组扩张2次例数比较,差异无统计学意义(P>0.05),研究组扩张3次例数低于对照组,研究组扩张1次例数高于对照组,差异有统计学意义(P<0.05);研究组治疗效果和手术结果优于对照组(P<0.05);治疗后,研究组炎性因子水平和并发症发生率低于对照组(P<0.05)。结论对食管癌放疗后狭窄患者行内镜直视下球囊扩张效果理想,可降低患者扩张次数,缩短手术时间,降低炎症因子水平,同时具有较高的安全性。因此,内镜直视下球囊扩张治疗食管癌放疗后狭窄,应在临床上应进一步推广和应用。
Objective To investigate the clinical application of endoscopic direct optical balloon dilatation in the treatment of stenosis after radiotherapy for esophageal cancer.Methods A total of 46 patients with esophageal cancer radiotherapy in our hospital from January 2016 to January 2019 were enrolled.They were randomly divided into two groups.The control group underwent strip expansion treatment.The study group underwent endoscopic balloon dilatation.The number of expansions,treatment effects,surgical outcomes,inflammatory factor levels,and complication rates were compared between the two groups.Results There was no significant difference between the study group and the control group for 2 times of expansion(P>0.05).The number of expansions for 3 times in the study group was lower than that in the control group.The number of expansion for 1 time in the study group was higher than that in the control group,and the difference was statistically significant(P<0.05).The treatment effect and surgical outcome of the study group were better than those of the control group(P<0.05).After treatment,the inflammatory factor level and complication rate of the study group were lower than those of the control group(P<0.05).Conclusion For patients with stenosis after radiotherapy for esophageal cancer,endoscopic direct optical balloon dilatation is effective,which reduces the number of patients' expansion,reduces the operative time,decreases the level of the inflammatory factor,and has higher safety.Therefore,endoscopic direct optical balloon dilatation for the treatment of stenosis after radiotherapy for esophageal cancer should be further promoted and applied clinically.
作者
叶晓丹
王小忠
许选
YE Xiaodan;WANG Xiaozhong;XU Xuan(Endoscopic Center,Shantou Central Hospital in Guangdong Province,Shantou 515041,China)
出处
《中国现代医生》
2019年第21期9-12,共4页
China Modern Doctor
基金
广东省汕头市科学技术局项目(181227104011276)
关键词
内镜直视
球囊扩张
食管癌放疗
吻合口狭窄
扩张次数
Endoscopic direct optical
Balloon dilation
Esophageal cancer radiotherapy
Anastomotic stenosis
Expansion times
