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急性肠炎治疗中阿奇霉素合理应用的临床疗效分析 被引量:4

Clinical Analysis of Rational Application of Azithromycin in the Treatment of Acute Enteritis
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摘要 目的探究急性肠炎治疗中阿奇霉素合理应用的临床疗效。方法据该院资料显示,在2016年1月-2017年1月期间共接诊治疗过80例急性肠炎患者。经患者及患者家属同意后将其随机分成观察组和对照组,每组40例患者。对照组患者给予静脉滴注阿奇霉素治疗,观察组患者根据病情状况及阿奇霉素药理机制进行口服或静脉滴注治疗。治疗结束后,医护人员将两组患者的治疗有效率、患者阿奇霉素用药安全性及患者生活质量进行详细记录并对比。结果观察组患者治疗有效率为(97.5%),对照组患者治疗有效率为(85.0%),观察组患者治疗有效率明显高于对照组患者治疗有效率,数据差异有统计学意义(χ^2=4.135,P=0.051);观察组患者不良反应发生率为(2.5%),对照组患者不良反应发生率为(20.0%),观察组患者不良反应发生率明显低于对照组患者不良反应发生率,数据差异有统计学意义(χ^2=2.956,P=0.051);观察组患者治疗前SAS评分为(62.41±4.15)分,SDS评分为(61.22±3.69)分,对照组患者治疗前SAS评分为(62.79±4.12)分,SDS评分为(63.49±4.11)分,观察组患者治疗后SAS评分为(26.49±3.96)分,SDS评分为(26.49±4.12)分,对照组患者治疗后SAS评分为(35.47±4.36)分(P>0.05),SDS评分为(33.14±5.71)分(P<0.05)。结论在急性肠炎治疗中合理应用阿奇霉素能够有效提高患者治疗有效率,降低患者不良反应发生率,缓解患者焦虑抑郁的负面情绪,促进患者病情恢复,值的在急性肠炎患者的治疗中被广泛推广使用。 Objective To explore the clinical efficacy of rational application of azithromycin in the treatment of acute enteritis.Methods According to the data of our hospital,80 patients with acute enteritis were treated and treated from January 2016 to January 2017.After the patient and the patient’s family agreed,they were randomly divided into observation group and control group,40 patients in each group.The patients in the control group were treated with intravenous azithromycin.The patients in the observation group were treated with oral or intravenous drip according to the condition and the pharmacological mechanism of azithromycin.After the treatment,the medical staff recorded and compared the treatment efficiency of the two groups of patients,the safety of azithromycin medication and the quality of life of the patients.Results The effective rate of treatment in the observation group was(97.5%),and the effective rate in the control group was(85.0%).The effective rate of treatment in the observation group was significantly higher than that in the control group The difference was statistically significant(χ~2=4.135,P=0.051).The incidence of adverse reactions was observed in the observation group(2.5%),and the incidence of adverse reactions in the control group(20.0%).The incidence of adverse reactions in the observation group was significantly lower than that in the control group,the data difference was statistically significant(χ~2=2.956,P=0.051);in the observation group,the pre-treatment SAS score was(62.41±4.15)points,the SDS score was(61.22±3.69)points,and the control group had the pre-treatment SAS score(62.79±4.12)points,SDS score was(63.49±4.11)points(P>0.05).The SAS score of the observation group was(26.49±3.96)points,the SDS score was(26.49±4.12)points,and the SAS score of the control group was(35.47±4.36)points,and the SDS score was(33.14±5.71)points(P<0.05).Conclusion The rational application of azithromycin in the treatment of acute enteritis can effectively improve the efficiency of patients�
作者 刘全伟 LHJ Quan-wei(Department of Liver Diseases, Spleen and Gastroenterology, Xintai City Hospital of Traditional Chinese Medicine, Xintai, Shandong Province, 271200 China)
出处 《系统医学》 2019年第14期67-69,共3页 Systems Medicine
关键词 急性肠炎 阿奇霉素 合理应用 疗效分析 Acute enteritis Azithromycin Rational application Efficacy analysis
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