摘要
雷公藤是我国传统中草药中的一块瑰宝,贵在其毒,是我国传统中草药中毒性最强的药物之一,民间很早有用雷公藤防治各种虫害、灭鼠、毒蛆等的记载。雷公藤,作为植物源杀鼠剂,其毒理学与毒代动力学方面的基础研究尚显薄弱,大量的有关雷公藤的毒副作用,其毒性成分、中毒机理以及预防与减毒措施等的研究均是以人用药物为目标进行开展的。本文对雷公藤作为植物源杀鼠剂类生物农药的开发利用的进展进行了综述。
The toxicity of Tripterygium wilfordii is very high.In fact, it is one of the most poison traditional Chinese herbal medicines in China.It has long been used to prevent and control various insects, rodents and mites.However, T.wilfordii,as a botanical rodenticide,has still very weak research background on toxicology and toxicokinetics.A large number of investigations about the toxic side effects of T.wilfordii,its toxic components,poisoning mechanism,and prevention and attenuation measures,were carried out with the goal of using as human drugs.The progress of T.wilfordii as botanical rodenticide,has been reviewed.
作者
汤鲁宏
TANG Lu-hong(School of Pharmaceutical Science, Jiangnan University, Wuxi 2\4\22, China)
出处
《中华卫生杀虫药械》
CAS
2019年第4期301-306,共6页
Chinese Journal of Hygienic Insecticides and Equipments
基金
国家“十二五”重点科技工程项目(编号:2011BAP16316-3-5)
科技部2012年农业(生物农药)成果转化项目(国科发[2012]821号)
关键词
雷公藤
植物源杀鼠剂
毒性
Tripterygium wilfordii
botanical rodenticide
toxicity
