摘要
目的对某医院近5年来收治的手足口病患儿特点与病原学特征进行研究。方法选择自2012年1月-2017年1月在医院进行治疗的疑似手足口病患儿490例,经过临床确诊445例作为研究对象。通过临床资料观察手足口病感染的流行病学特点,分析病菌分布情况和病原学特征并对手足口病感染发生的影响因素进行分析。结果所有年龄段和不同性别的患儿中EV-71病毒感染占比较大(P<0.05);春季患儿的EV-71病毒感染占比较大,夏季患儿的CoxA16病毒感染占比较大,秋、冬季节以其他类型病毒感染者为主,(P<0.05)。重症和普通患儿感染病毒类型均为EV-71;家庭卫生条件较差、饮水条件较差和与手足口病患儿有过接触是手足口病感染的主要影响因素(P<0.05);家庭卫生条件、饮水条件、与手足口病患儿有过接触是手足口病感染的独立危险因素(P<0.05)。结论 EV-71感染是患儿的主要病毒感染类型;根据季节不同其病原体有着明显区别;家庭卫生状况、饮水条件、是否与手足口病患儿有过接触是影响手足口病感染发生的独立危险因素。
OBJECTIVE To investigate the epidemiological characteristics and etiological features of children with hand, foot and mouth disease in a hospital in the past 5 years. METHODS A total of 490 children with suspected hand, foot and mouth disease who were treated in the hospital from Jan 2012 to Jan 2017 were enrolled in the study, 445 of whom were clinically diagnosed with hand, foot and mouth disease. The epidemiological characteristics of hand, foot and mouth disease were observed by means of review of clinical data, the distribution of pathogens and etiological features were analyzed, and the influencing factors for the hand, foot and mouth disease were observed. RESULTS The children who had EV-71 infection were dominant among the children of all age groups and genders(P<0.05). The EV-71 infection was prevalent in spring, CoxA16 virus infection was prevalent in summer, and the infections with other species of viruses were prevalent in autumn and winger(P<0.05). Both the critically ill children and common children had the EV-71 infection. The poor sanitary condition at home, poor drinking condition and history of contact with hand, foot and mouth disease children were the major influencing factors for the hand, foot and mouth disease(P<0.05). The sanitary condition at home, drinking condition and history of contact with hand, foot and mouth disease children were the independent risk factors for the hand, foot and mouth disease(P<0.05). CONCLUSION EV-71 is the predominant species of virus among children and differ remarkably with other pathogens in seasons. The sanitary condition at home, drinking condition and history of contact with hand, foot and mouth disease children are the independent risk factors for the hand, foot and mouth disease.
作者
刘健
闫秀丽
谢忠侠
黄舒华
许传英
LIU Jian;YAN Xiu-li;XIE Zhong-xia;HUANG Shu-hua;XU Chuan-ying(Central Hospital of Shanxian County , Heze, Shandong 274300, China)
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2019年第13期2037-2040,共4页
Chinese Journal of Nosocomiology
基金
菏泽市医药卫生科技发展计划基金资助项目(27929370)
关键词
手足口病感染
流行病学
病原学
单因素
多因素
Hand,foot and mouth disease
Epidemiology
Etiology
Univariate
Multivariate
