摘要
目的探讨早期糖尿病肾病尿微量白蛋白与肌酐比值的检测在临床诊断中的价值,为临床实践总结经验。方法方便选择该院收治的900例糖尿病肾病患者纳入到该次研究对象当中,作为该次研究的观察组,同时选择在该院体检的900名健康者作为对照组进行研究,研究对象纳入时间为2017年1月—2018年6月,对比两组的尿微量白蛋白与肌酐比值,同时比较两组的阳性率。结果观察组的尿微量白蛋白检测值为(108.18±52.73)mg/L明显高于对照组(18.37±5.68)mg/L(t=5.325;P<0.05);观察组的肌酐检测值为(63.85±8.81)μmol/L明显高于对照组(11.43±3.57)μmol/L(t=4.854;P<0.05);观察组的尿微量白蛋白与肌酐比值为(2.83±1.16)mg/mmol也明显高于对照组(1.75±0.29)mg/mmol,差异有统计学意义(t=3.658;P<0.05);观察组中,尿蛋白阳性例数为220例、阳性率为24.44%,mAlb阳性例数为523例、阳性率为58.11%,对照组中,尿蛋白阳性例数为0例、阳性率为0.00%,mAlb阳性例数为9例、阳性率为10.00%,两组的尿蛋白及mAlb阳性率比较,差异有统计学意义(P<0.05)。结论尿微量白蛋白与肌酐比值在早期糖尿病肾病的诊断中有着重要的作用,有利于尽早发现糖尿病肾病,能够为临床诊断提供可靠的依据,有着较高的临床应用价值。
Objective To investigate the value of the detection of urine microalbumin and creatinine ratio in early diabetic nephropathy in clinical diagnosis,and to summarize the experience in clinical practice.Methods Convenient select a total of 900 patients with diabetic nephropathy admitted to our hospital were enrolled in this study.As the observation group of this study,900 healthy subjects in our hospital were selected as the control group.The study time was from January 2017 to June 2018,the ratio of urinary albumin to creatinine was compared between the two groups,and the positive rates of the two groups were compared.Results The detection value of urinary albumin in the observation group was(108.18±52.73)mg/L significantly higher than that in the control group(18.37±5.68)mg/L(t=5.325;P<0.05).The creatinine detection value of the observation group was(63.85±8.81)μmol/L was significantly higher than the control group(11.43±3.57)μmol/L(t=4.854;P<0.05);the ratio of urinary albumin to creatinine in the observation group was(2.83±1.16)mg/mmol,significantly higher than the control group(1.75±0.29)mg/mmol,the difference was statistically significant(t=3.658;P<0.05).In the observation group,the number of positive urine protein was 220,the positive rate was 24.44%,and the mAlb was positive cases of 523,and the positive rate was 58.11%.In the control group,the number of urinary protein positive cases was 0,the positive rate was 0.00%,the number of mAlb positive cases was 9 cases,and the positive rate was 10.00%.There was a significant difference between the positive rate of mAlb and the positive rate of mAlb(P<0.05).Conclusion The ratio of microalbuminuria to creatinine plays an important role in the diagnosis of early diabetic nephropathy,which is helpful for early detection of diabetic nephropathy.It can provide a reliable basis for clinical diagnosis and has high clinical application value.
作者
冯恩航
FENG En-hang(Department of Laboratory Diagnosis,Heilongjiang Provincial Hospital,Harbin,HeilongjiangProvince,150036 China)
出处
《中外医疗》
2019年第19期168-170,共3页
China & Foreign Medical Treatment
关键词
尿微量白蛋白
肌酐
糖尿病肾病
临床诊断
阳性率
Urinary microalbumin
Creatinine
Diabetic nephropathy
Clinical diagnosis
Positive rate
