摘要
目的探讨实时剪切波弹性成像(SWE)应用于股总静脉血栓(CFVT)临床分期的价值。方法根据主诉发病时间将92例单侧CFVT患者分为急性期(1~14天,n=41)、亚急性期(15~30天,n=24)及慢性期(>30天,n=27),比较其二维超声评分及SWE所测杨氏模量值。采用ROC曲线评价二维超声及SWE对急性期、慢性期CFVT的诊断效能。结果3期患者间二维超声评分及杨氏模量值总体比较(P均<0.001)及两两比较差异均有统计学意义(P均<0.05)。以杨氏模量值=13.50kPa为截断值,SWE诊断急性期CFVT的AUC为0.916(P<0.05),敏感度85.37%,特异度82.35%;以二维超声评分=2.00为截断值,二维超声诊断急性期CFVT的AUC为0.800(P<0.05),敏感度75.61%,特异度66.67%;2种方法AUC差异有统计学意义(P<0.001)。以杨氏模量值=16.40kPa为截断值,SWE诊断慢性期CFVT的AUC为0.917(P<0.05),敏感度85.19%,特异度87.69%;以二维超声评分=2.03为截断值,二维超声诊断慢性期CFVT的AUC为0.842(P<0.05),敏感度87.21%,特异度69.23%;两种方法AUC差异有统计学意义(P=0.010)。结论SWE可用于判断CFVT临床分期,且效果好于常规超声。
Objective To explore the value of real-time shear wave elastography (SWE) in staging of common femoral venous thrombosis (CFVT). Methods Totally 92 patients with unilateral CFVT were divided into acute phase (1-14 d, n =41), subacute phase (15-30 d, n =24) or chronic phase (>30 d, n =27) according to the time of complaint. Young's modulus mean values and two-dimensional (2D) ultrasound scores were compared among the three phases. ROC curve was used to evaluate the diagnostic effect of 2D ultrasound and SWE for acute and chronic CFVT. Results 2D ultrasound scores and Young's modulus values were significantly different among the three phases ( P <0.001), and the differences between each two phases were all statistically significant (all P <0.05). AUC of SWE in diagnosing acute CFVT was 0.916 ( P <0.05), and the cutoff Young's modulus value was 13.50 kPa, with the sensitivity of 85.37% and specificity of 82.35%. AUC of 2D ultrasound for diagnosing acute CFVT was 0.800 ( P <0.05), and the cutoff ultrasound score was 2.00, with the sensitivity of 75.61% and specificity of 66.67%. AUC of the two methods for diagnosing acute CFVT had significant difference ( P <0.001). AUC of SWE in diagnosing chronic CFVT was 0.917 ( P <0.05), and the cutoff Young's modulus value was 16.40 kPa, with the sensitivity of 85.19% and specificity of 87.69%. AUC of 2D ultrasound in diagnosing chronic CFVT was 0.842 ( P <0.05), and the cutoff ultrasound score was 2.03, with the sensitivity of 87.21% and specificity of 69.23%. AUC of these two methods for diagnosing chronic CFVT had significant difference ( P = 0.010). Conclusion Real-time SWE can be used to judge the clinical stage of CFVT, and its diagnostic efficiency may be better than conventional ultrasonography.
作者
洪登科
杨嘉嘉
薛恩生
张宇
官云彪
李南
HONG Dengke;YANG Jiajia;XUE Ensheng;ZHANG Yu;GUAN Yunbiao;LI Nan(Department of Vascular Surgery, Fujian Medical University Union Hospital, Fuzhou 350001, China;Department of Ultrasound, Fujian Medical University Union Hospital, Fuzhou 350001, China)
出处
《中国医学影像技术》
CSCD
北大核心
2019年第8期1200-1204,共5页
Chinese Journal of Medical Imaging Technology
基金
福建省卫计委青年基金项目(2015-2-9)
关键词
静脉血栓形成
股静脉
剪切波
弹性成像技术
超声检查
venous thrombosis
femoral vein
share wave
elasticity imaging techniques
ultrasonography
