摘要
早产低出生体重儿在生长发育过程中容易发生发育迟缓、传染病等并发症,且病死率较健康新生儿高,属于高危儿。流行病学等资料表明孕妇牙周病与早产低出生体重儿具有一定相关性,孕妇牙周病是早产低出生体重儿等不良妊娠结局的危险因素之一,本文就孕妇牙周病与早产低出生体重儿的相关性、牙周治疗对早产低出生体重儿发生率的影响,以及孕妇牙周病引发早产低出生体重儿的相关机制作一综述。本文综述结果表明,目前的研究证实孕妇牙周病与早产低出生体重儿的相关性,但未完全阐明两者的因果关系以及具体的机制和途径,可能的机制为孕妇牙周致病菌通过胎盘屏障进而影响妊娠结局。因此,还需对其两者关系具体的机制、途径以及干预治疗等进行更深入的研究。
Preterm low birth weight newborns are prone to complications during growth and development,such as growth retardation and infectious diseases,and the mortality rate of high-risk infants is higher than that of healthy newborns.Epidemiological data show that periodontal disease in pregnant women is correlated with preterm low birth weight.Periodontal disease in pregnant women is one of the risk factors for adverse pregnancy outcomes,such as preterm low birth weight.This paper addresses the correlation between maternal periodontal disease and preterm low birth weight,the influence of periodontal treatment on the incidence of preterm low birth weight,and premature birth caused by maternal periodontal disease.The mechanism of infant weight is reviewed.The results of this review show that the current studies confirm the correlation between maternal periodontal disease and pretermlow birth weight.However,the causal relationship between maternal periodontal disease and preterm low birth weight is not fully elucidated,and the specific mechanism and approach are not clear.A possible mechanism is that periodontal pathogens in pregnant women pass through the placental barrier to influence pregnancy outcomes.Therefore,more in-depth research is needed on the specific mechanism,approach,intervention and treatment based on the relationship between these two factors.
作者
夏凤娟
申晓青
XIA Fengjuan;SHEN Xiaoqing(Department of Stomatology,Zhujiang Hospital,Southern Medical University,Guangzhou 510000,China)
出处
《口腔疾病防治》
2019年第8期541-544,共4页
Journal of Prevention and Treatment for Stomatological Diseases
基金
广东省自然科学基金项目(2014A030313330)
关键词
孕妇
早产低出生体重儿
牙周病
牙周致病菌
感染
牙周治疗
pregnant women
preterm low birth weight
periodontal disease
periodontal pathogen
infection
periodontal treatment
