摘要
目的分析肺表面活性物质联合CPAP对呼吸窘迫综合征新生儿血气指标的影响。方法2015年1月至2018年12月,我院共接收60例新生儿呼吸窘迫症患儿,根据数字法进行随机分组,观察组30例,给予患儿CPAP+肺表面活性物质治疗。对照组30例,给予患儿CPAP治疗。比较两组患儿的治疗效果、治疗前治疗后肺动脉血气指标、OI指数。结果(1)观察组治疗有效率比对照组高,其中观察组有效率为93.33%,对照组有效率为50.00%,P<0.05。(2)两组各自治疗前后对比,治疗后P(CO2)水平明显降低,P(O2)水平、OI指数明显升高,P<0.05。两组治疗前对比无差异,P>0.05。观察组治疗后P(CO2)水平明显更低,P(O2)、OI指数明显更高,P<0.05。两组治疗后PH无差异,P>0.05。结论对新生儿窘迫症患儿实施肺表面活性物质和持续气道正压通气(CPAP)联合治疗方法,可以更有效改善患者肺动脉血气状况,有利于提高治疗效果。
Objective To analyze the effect of lung surfactant combined with CPAP on blood gas index of newborns with respiratory distress syndrome.Methods From January 2015 to December 2018,60 cases of neonatal respiratory distress were received in our hospital,and 30 cases were randomly grouped according to the digital method. CPAP + pulmonary surfactant were treated in the observation group.In control group,30 patients were treated with CPAP.To compare the therapeutic effect,pulmonary artery blood gas index and OI index of two groups of children. Results (1) The treatment efficiency of the observation group was higher than that of the control group,of which the effective group was 93.33 %,the effective group was 50.00 %,P<0.05.(2) The two groups were compared before and after the treatment,the P(CO2) level was significantly reduced,the P(O2) level and the OI index were significantly increased,P<0.05.There was no difference between the two groups before treatment,P>0.05.The levels of P(CO2) were significantly lower,P(O2) and OI were significantly higher,P<0.05.There was no difference in PH after treatment between the two groups,P<0.05.Conclusion The combined treatment of pulmonary surfactant and continuous positive airway pressure(CPAP) can improve the pulmonary arterial blood gas condition and improve the therapeutic effect.
作者
高雪亚
GAO Xue-ya(Jining Women's and Children's Hospital,Jining,Shandong 272000)
出处
《智慧健康》
2019年第17期110-111,共2页
Smart Healthcare
