摘要
目的:观察保乳术与改良根治术治疗早期乳腺癌的临床疗效及对血清肿瘤标志物的影响。方法:选择早期乳腺癌患者104例,依据随机数表法将其分为两组,每组各52例。观察组接受保乳手术治疗,对照组接受改良根治术治疗。观察两组围手术期指标、血清肿瘤标志物[糖类抗原153(CA153)、癌胚抗原(CEA)]水平。结果:观察组术中出血量较少,手术时间、住院时间较短,与对照组比较差异有统计学意义(P<0.05);手术前和术后两组间CA153、CEA水平比较差异无统计学意义(P>0.05)。结论:早期乳腺癌患者接受保乳术及改良根治术治疗均利于降低血清CA153、CEA水平,但保乳术治疗损伤小,可缩短住院时间。
Objective:To observe the clinical efficacy of breast-conserving surgery and modified radical mastectomy in the treatment of early breast cancer and its effect on serum tumor markers. Methods:104 patients with early breast cancer were enrolled. According to the random number table method, they were divided into two groups, 52 cases in each group. The observation group received breast-conserving surgery and the control group received modified radical mastectomy. Perioperative indicators, serum tumor markers [carbohydrate antigen 153(CA153), carcinoembryonic antigen(CEA)] levels were observed. Results:The intraoperative blood loss, operation time and hospitalization time in the observation group were lower than those in the control group, and the difference was statistically significant(P<0.05). There was no significant difference in the levels of CA153 and CEA between the two groups before and after surgery(P>0.05). Conclusion: Early breast cancer patients undergoing breast-conserving surgery and modified radical mastectomy are beneficial to reduce serum CA153 and CEA levels. However, breast-conserving surgery has less damage and is beneficial to shorten hospital stay.
作者
张建良
ZHANG Jianliang(Department ofGeneral Surgery, The First People' s Hospital of Nanyang City, Nanyang 473000, China)
出处
《华夏医学》
CAS
2019年第3期110-113,共4页
Acta Medicinae Sinica
关键词
乳腺癌
保乳术
改良根治术
血清肿瘤标志物
breast cancer
breast-conserving surgery
modified radical mastectomy
serum tumor markers
