摘要
目的探讨胎盘部分植入及粘连的患者应用米非司酮予以治疗效果及预后。方法选择我院2017年3月—2018年3月收治胎盘部分植入及粘连的患者100例作为研究对象,将其随机分为两组。对照组50例应用缩宫素20U静脉滴注方案治疗;观察组50例采用米非司酮口服方案治疗。两组患者的总有效率、预后等展开对比。结果观察组患者的治疗总有效率高于对照组,产后72h出血量低于对照组,用药7d内大块胎盘排出,阴道流血停止率均高于对照组,差异均具有统计学意义(P<0.05)。观察组未见明显不良反应,对照组不良反应发生率为4%,组间比较,差异无统计学意义(P>0.05)。结论胎盘部分植入及粘连的患者,应用米非司酮予以治疗,可显著提高治疗效果。
Objective To investigate the therapeutic effect and prognosis of mifepristone in patients with partial placenta implantation and adhesion. Methods 100 patients with partial placenta implantation and adhesion in our hospital from March 2017 to March 2018 were selected as the study subjects and randomly divided into two groups. 50 cases in the control group were treated with intravenous drip of oxytocin 20 U. In the observation group, 50 cases were treated with mifepristone oral regimen. The total effective rate and prognosis of the two groups were compared. Results The total effective rate of treatment in the observation group was higher than that in the control group. The amount of postpartum hemorrhage 72 hours was lower than that in the control group. Within 7 days of medication, massive placenta was discharged, and the stop rate of vaginal bleeding was higher than that in the control group. The difference was statistically significant (P < 0.05). There were no significant adverse reactions in the observation group. The incidence of adverse reactions in the control group was 4%. There was no significant difference between the two groups (P > 0.05). Conclusion Mifepristone can significantly improve the therapeutic effect in patients with partial placenta implantation and adhesion.
作者
谷金富
谭虹
GU Jinfu;TAN Hong(Department of Obstetrics, Yafeiya Obstetrics and Gynecology Hospital, Enshi Hubei 445000, China)
出处
《中国继续医学教育》
2019年第21期118-120,共3页
China Continuing Medical Education
关键词
胎盘植入
胎盘粘连
米非司酮
总有效率
产后出血量
阴道流血停止时间
placenta implantation
placental adhesion
mifepristone
total effective rate
postpartum hemorrhage
vaginal bleeding stop time
