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清火健脾丸对肝胃郁热型慢性萎缩性胃炎的临床疗效研究 被引量:2

Clinic Study of Qinghuojianpi Pill in Treatment of Chronic Atrophic Gastritis with Heat Accumulation in Liver and Stomach
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摘要 目的探讨清火健脾丸在治疗肝胃郁热型慢性萎缩性胃炎中的临床价值。方法对我院2015年1月至2016年1月期间明确诊断的80例慢性萎缩性胃炎患者临床资料进行回顾性分析,纳入研究的患者资料分为治疗组和对照组,每组各40例。治疗组采用单纯清火健脾丸治疗,对照组治疗联合使用多潘立酮和果胶秘,两组方案治疗维持8周,观察指标包括治疗组和对照组的疗效积分、Hp根除率和中医证候积分。结果较对照组而言,清火健脾丸组治疗后的临床疗效积分和Hp清除率显著高于对照组,二者有统计学差异(P<0.05);清火健脾丸组治疗后中医证候积分显著低于对照组(P<0.05),清火健脾丸组的临床治疗效果显著高于对照组。结论肝胃郁热型慢性萎缩性胃炎患者采用清火健脾丸治疗能取得较好的临床效果,尤其能够显著提高患者Hp清除率,值得临床进一步推广应用。 Objective To discuss the clinical effect of Qinghuojianpi pill in treatment of chronic atrophic gastritis with heat accumulation in liver and stomach. Methods 80 cases in our hospital form January 2015 to January 2016 were randomly divided into two groups: treatment group with 40 cases were underwent by Qinghuojianpi pill, thus control group also with 40 cases were underwent by domperidone and colloidal bismuth pectin capsules for 2 month respectively. Compare clinical efficacy integral, Hp clearance rate and TCM syndrome integral between treatment group and the control group. Results The clinical efficacy integral and Hp clearance rate of the treatment group were significantly higher than those of the control group (P< 0.05), while TCM syndrome integral in the treatment group with Qinghuojianpi pill was significantly lower than that of control group with domperidone and colloidal bismuth pectin capsules. The clinical effect of the treatment group was significant superior than that of the control group. Conclusion Qinghuojianpi pill can achieve a significant clinical effect on CAG patients with heat accumulation in liver and stomach of chronic atrophic gastritis and especially reduce the Hp clearance rate of CAG patients in order to exert its therapeutic effect.
作者 袁欣 YUAN Xin(PLA 31614 Military Hospital, Xiamen 361005, China)
机构地区 中国人民解放军
出处 《中国医药指南》 2019年第20期1-3,共3页 Guide of China Medicine
关键词 清火健脾丸 慢性萎缩性胃炎 临床研究 Qinghuojianpi pill Chronic atrophic gastritis Clinical study
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