摘要
神经损伤在临床中较为常见,探索有效修复损伤神经的方法已经成为近年来的研究热点。干细胞源外泌体(SC-exosomes)内含多种生物活性物质。干细胞能发挥各种组织修复作用主要依赖于其分泌的外泌体。本文就SC - exosomes的生物学特性及其对神经损伤修复的影响做一综述。
Nerve injury is common in clinic. Stem cell derived exosomes ( SC - exosomes) contains a variety of bioactive substances in vivo. Exploring effective methods for repairing injured nerves has become a research hotspot in recent years. Muliple reports showed that stem cells play a variety of roles in tissue repair mainly depending on their secreted exosomes. This paper reviews the biologicalcharacteristics of stem cell - derived exosomes and their effects on the repair of nerve injury in order.
作者
朱佳敏
刘玉梅
张自强
李晓宁
张昊恺
曹雨露
ZHU Jia-min;LIU Yu-mei;ZHANG Zi-qiang;LI Xiao-ning;ZHANG Hao-kai;CAO Yu-lu(College of Animal Science and Technology,Henan University of Science and Technology,Luoyang 471023,Henan Province,China)
出处
《中国临床药理学杂志》
CAS
CSCD
北大核心
2019年第13期1413-1416,共4页
The Chinese Journal of Clinical Pharmacology
基金
国家自然科学基金资助项目(U1504325)
