摘要
主动脉夹层是一种死亡率极高的疾病,主动脉CT血管造影是临床诊断主动脉夹层的“金标准”,但该检查存在辐射、造影剂过敏、肾功能损伤等风险,且诊断阳性率并不高。研究发现主动脉夹层相关循环生物标志物(D-二聚体及年龄调整后D-二聚体、基质金属蛋白酶、可溶性人基质裂解素2等)有望为主动脉夹层的筛查提供帮助。现对主动脉夹层及其相关循环生物标志物做一简要综述。
Aortic dissection is a disease with a very high mortality rate. CT angiography of aorta is the “gold standard” of aortic dissection, but it has risks such as radiation, allergy of contrast agent,and damage of renal function,and low positive rate. Recent studies showed that aortic dissection related circulatory biomarkers such as D-dimer and age-adjusted D-dimer, matrix metalloproteinase, and soluble human matrix lyase 2, is expected to provide help for screening aortic dissection. This paper briefly reviews aortic dissection and related circulatory biomarkers.
作者
岳增旭
孔一慧
YUE Zengxu;KONG Yihui(Department of Cardiology, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, Heilongjiang,China)
出处
《心血管病学进展》
CAS
2019年第4期595-598,共4页
Advances in Cardiovascular Diseases
