摘要
目的探讨无创正压通气救治慢性阻塞性肺疾病并呼吸衰竭的临床疗效。方法选取134例于2015年1月至2018年10月在本院进行治疗的慢性阻塞性肺疾病并呼吸衰竭患者,依治疗方法不同将其分为对照组和研究组,对照组行常规综合治疗,研究组于对照组基础上加施无创正压通气治疗,观察并比较两组患者的治疗效果。结果两组患者治疗前的pH、PaCO2及PaO2水平比较差异无统计学意义,治疗后均有所改善,研究组治疗后各项动脉血气指标均明显优于对照组,组间比较差异有统计学意义(P<0.05);研究组患者治疗总有效率为89.55%,明显高于对照组73.13%,组间比较差异有统计学意义(P<0.05);经为期6个月的随访,研究组患者不良事件的发生率为14.93%,明显低于对照组的31.34%,组间比较差异有统计学意义(P<0.05)。结论给予慢性阻塞性肺疾病并呼吸衰竭患者无创正压通气治疗可有效纠正患者动脉血气指标,提高治疗效果,减少不良事件的发生,值得在临床当中推广应用。
Objective To investigate the clinical efficacy of noninvasive positive pressure ventilation in the treatment of chronic obstructive pulmonary disease with respiratory failure.Methods A total of 134 patients with chronic obstructive pulmonary disease and respiratory failure who were treated in our hospital from January 2015 to October 2018 were enrolled.The patients were divided into the control group and the study group according to different treatment methods.The study group was treated with noninvasive positive pressure ventilation on the basis of the control group,and the therapeutic effects of the two groups were observed and compared.Results There was no significant difference in pH,PaCO2 and PaO2 levels between the two groups before treatment.All the patients were improved after treatment.The arterial blood gas indexes of the study group were significantly better than the control group(P<0.05);the total effective rate of the study group was 89.55%,which was significantly higher than that of the control group(73.13%).There was significant difference between the two groups(P<0.05).After 6 months follow-up,the study group The incidence of adverse events was 14.93%,which was significantly lower than that of the control group(31.34%).There was significant difference between the two groups(P<0.05).Conclusion Non-invasive positive pressure ventilation in patients with chronic obstructive pulmonary disease and respiratory failure can effectively correct the arterial blood gas index,improve the treatment effect and reduce the occurrence of adverse events.It is worthy of popularization and application in clinical practice.
作者
胡明森
徐艳
姚丽丽
Hu Mingsen;Xu Yan;Yao Lili(Department of Intensive Medicine,Center Hospital of Rizhao,Rizhao,Shandong,276800,China)
出处
《当代医学》
2019年第22期80-83,共4页
Contemporary Medicine
关键词
无创正压通气
慢性阻塞性肺疾病
呼吸衰竭
Non-invasive positive pressure ventilation
Chronic obstructive pulmonary disease
Respiratory failure
