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重组人干扰素α-2b注射液雾化吸入联合山蜡梅叶颗粒治疗小儿疱疹性咽峡炎疗效分析 被引量:20

Therapeutic effect of recombinant human interferon α-2b injection inhalation combined with Shanxi wax Meiye granule on children with herpetic angina
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摘要 目的研究山蜡梅叶颗粒与重组人干扰素α-2b注射液雾化吸入联合治疗小儿疱疹性咽峡炎的临床效果。方法选取2017年1月至2018年7月本院疱疹性咽峡炎患儿162例,依照治疗方案不同分为观察组和对照组,各81例。对照组采用常规治疗,观察组在对照组基础上采用山蜡梅叶颗粒+重组人干扰素α-2b注射液雾化吸入治疗。比较两组疗效、咽峡部疱疹消退时间、退热时间、流涎疼痛消失时间、住院时间,对比两组治疗前后免疫功能指标[免疫球蛋白A(IgA)、IgM、IgG]。结果观察组总有效率(98.77%)较对照组(90.12%)高(P<0.05);观察组咽峡部疱疹消退时间、退热时间、流涎疼痛消失时间、住院时间短于对照组(P<0.05);治疗后,观察组IgG高于对照组,IgA、IgM低于对照组(P<0.05)。结论山蜡梅叶颗粒与重组人干扰素α-2b注射液雾化吸入联合治疗小儿疱疹性咽峡炎疗效显著,能有效促进患儿症状缓解,缩短住院时间,改善免疫功能。 Objective To research the clinical effect of the combination of Shanqimeiye granules and recombinant human interferon α-2b injection in the treatment of herpes simplex angina. Methods Selecting 162 children with herpetic angina in our hospital from January 2017 to July 2018, According to different treatment options, it was divided into observation group and control group, 81 cases in each group, The control group was treated with conventional therapy, and the observation group was treated with the inhalation treatment of the mountain wax mei granule + recombinant human interferon α-2b injection on the basis of the control group.The efficacy of the two groups, the time of disappearance of pharyngeal herpes, the time of fever, the time of disappearance of salivation pain, and the length of hospital stay were compared. The immunological function indicators [immunoglobulin A (IgA), IgM, IgG] were compared before and after treatment. Results The total effective rate of the observation group (98.77%) was higher than that of the control group (90.12%)(P<0.05);In the observation group, the time of herpes remission, the time of fever, the disappearance time of salivation pain, and the hospitalization time were shorter than the control group (P<0.05). After treatment, the IgG of the observation group was higher than that of the control group, and IgA and IgM were lower than the control group (P<0.05). Conclusion The combination of Waxanthus chinensis granules and recombinant human interferon α-2b injection in the treatment of herpes simplex angina is effective in promoting symptom relief, shortening hospital stay and improving immune function.
作者 许景怀 易亮 林浩杰 Xu Jinghuai;Yi Liang;Lin Haojie(Pediatrics,Luxi County Maternal and Child Health Hospital,Pingxiang,Jiangxi,337200,China)
出处 《当代医学》 2019年第21期83-85,共3页 Contemporary Medicine
关键词 山蜡梅叶颗粒 重组人干扰素α-2b注射液雾化吸入 小儿疱疹性咽峡炎 Mountain wax plum leaf granules Recombinant human interferon α-2b injection inhalation Pediatric herpes angina
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