摘要
目的分析经鼻同步间歇指令通气(nSIMV)联合TSP体位治疗早产儿呼吸暂停的临床疗效。方法选取2016年1月至2017年5月该院新生儿重症监护室住院的60例胎龄小于36周的原发性呼吸暂停早产儿为研究对象,分为nSIMV+TSP组、nSIMV组和经鼻持续气道正压通气(nCPAP)组,每组20例。比较各组患儿治疗前后2h血气分析结果、疗效、呼吸机使用时间、住院时间及胃肠道并发症。结果治疗后,nSIMV组和nSIMV+TSP组患儿PO2、SaO2明显高于nCPAP组(P<0.05),PCO2、每分钟呼吸暂停次数、心率下降次数、应用呼吸机时间、平均住院时间均明显低于nCPAP组,nSIMV组和nSIMV+TSP组间差异无统计学意义(P>0.05)。3组患儿治疗后腹胀、喂养不耐受等胃肠道不良反应差异无统计学意义(P>0.05)。结论 nSIMV联合TSP体位治疗早产儿呼吸暂停相较于nCPAP更有优势,而在改善氧合方面优于单独使用nSIMV。
Objective To analyze the clinical efficacy of nasal synchronized intermittent mandatory ventilation(nSIMV)combined with three-stair-position(TSP)in treating primary apnea of premature.MethodsSixty preterm neonates(gestational age<36 weeks)with primary apnea hospitalized in the neonatal intensive care unit of this hospital from January 2016 to May 2017 were selected and divided into the nSIMV + TSP group,nSIMV group and nCPAP group,with 20 cases in each group.The blood gas analysis results,therapeutic efficacy,ventilator use time,hospitalization time and gastric and intestinal complications before treatment and at 2 hafter treatment were compared among the three groups.Results PO2 and PCO2 after treatment in the nSIMV group and nSIMV+TSP group were significantly higher than those in the nCPAP group(P<0.05),while PCO2 and apnea times per min,times of heart rate decrease and average hospitalization time were significantly lower than those in the nCPAP group,and the difference between the nSIMV group and the nSIMV+TSP group had no statistical significance(P>0.05).The gastrointestinal adverse reactions of abdominal distension and feeding intolerance had no statistical difference among 3 groups(P>0.05).Conclusion nSIMV combined with TSP is superior to nCPAP for the treatment of apnea in preterm infants,and better than nSIMV in improvement of oxygenation.
作者
沈蕾蕾
任浩
陶敏
范文婷
胡影
SHEN Leilei;REN Hao;TAO Min;FAN Wenting;HU Ying(Department of Pediatrics,the First Affiliated Hospital of Army Medical University,Chongqing 400038,China)
出处
《重庆医学》
CAS
2019年第13期2250-2253,共4页
Chongqing medicine
关键词
呼吸暂停
TSP体位
经鼻同步间歇指令通气
连续气道正压通气
婴儿
早产
apnea
three-stair-position
nasal synchronized intermittent mandatory ventilation
continuous positive airway pressure
infant,premature
