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替格瑞洛对急性冠脉综合征伴复杂病变患者血管内皮功能及不良心血管事件的影响

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摘要 目的:探究伴复杂病变的急性冠脉综合征(ACS)患者应用替格瑞洛治疗的效果与安全性及对血管内皮功能的影响。方法:抽签法将95例ACS复杂病变患者分为2组,常规治疗基础上,对照组47例予阿司匹林,实验组48例加用替格瑞洛,均治疗3个月。对比两组疗效、不良心血管事件(MACE)情况,治疗前后患者血管内皮功能变化情况。结果:实验组总有效率及NO水平高于对照组,不良心血管事件发生率及ET-1水平低于对照组(均P<0.05)。结论:替格瑞洛可有效改善ACS复杂病变患者的血管内皮水平,减少不良MACE发生,效果良好。
作者 王艳艳
出处 《医学理论与实践》 2019年第13期2012-2013,共2页 The Journal of Medical Theory and Practice
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