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儿童炎症性肠病规范诊治面临的挑战 被引量：6

Challenges in the standardized diagnosis and treatment of pediatric inflammatory bowel disease
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摘要 我国儿童炎症性肠病(IBD)发病率不断增高。相对于成人,儿童IBD症状更重,不典型表现多,易延误诊断,因此危害更大。儿科医师应在共识的指导下,重视儿童IBD的特殊表现,及时诊断,合理利用检查全面评估患儿,并尽早启动规范化治疗,尽可能改善患儿生活质量。开展多中心临床研究和多组学的转化医学研究,将为儿童IBD的精准化治疗和个性化治疗开辟新的领域。
作者 肖园 许春娣 Xiao Yuan;Xu Chundi(Department of Pediatrics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai200025, China)
机构地区 上海交通大学医学院附属瑞金医院儿内科
出处 《中华儿科杂志》 CAS CSCD 北大核心 2019年第7期497-500,共4页 Chinese Journal of Pediatrics
关键词 炎症性肠病 儿童 多中心临床研究 规范化治疗 诊治 延误诊断 不典型表现 个性化治疗
分类号 R72 [医药卫生—儿科]
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  • 1Martina Galatola,Erasmo Miele,Caterina Strisciuglio,Lorella Paparo,Daniela Rega,Paolo Delrio,Francesca Duraturo,Massimo Martinelli,Giovanni Battista Rossi,Annamaria Staiano,Paola Izzo,Marina De Rosa.Synergistic effect of interleukin-10-receptor variants in a case of early-onset ulcerative colitis[J].World Journal of Gastroenterology,2013,19(46):8659-8670. 被引量：7
  • 2江米足,叶瑞云,欧弼悠,吴秀英,陈肖肖,陈洁,章许平.小儿纤维结肠镜检查操作常规（试行）[J].中华儿科杂志,1996,34(5):306-308. 被引量：18
  • 3Neil Shah,Jochen Kammermeier,Mamoun Elawad,Erik-Oliver Glocker.Interleukin-10 and Interleukin-10–Receptor Defects in Inflammatory Bowel Disease[J].Current Allergy and Asthma Reports.2012(5) 被引量：2
  • 4Holm H. Uhlig,Tobias Schwerd,Sibylle Koletzko,Neil Shah,Jochen Kammermeier,Abdul Elkadri,Jodie Ouahed,David C. Wilson,Simon P. Travis,Dan Turner,Christoph Klein,Scott B. Snapper,Aleixo M. Muise.The Diagnostic Approach to Monogenic Very Early Onset Inflammatory Bowel Disease[J]. Gastroenterology . 2014 被引量：3
  • 5Cheng Hiang Lee,Peter Hsu,Brigitte Nanan,Ralph Nanan,Melanie Wong,Kevin J. Gaskin,Rupert W. Leong,Ryan Murchie,Aleixo M. Muise,Michael O. Stormon.Novel de novo mutations of the interleukin-10 receptor gene lead to infantile onset inflammatory bowel disease[J]. Journal of Crohn’s and Colitis . 2014 被引量：2
  • 6Levine A,Koletzko S,Turner D,Escher JC,Cucchiara S,de Ridder L,Kolho KL,Veres G,Russell RK,Paerregaard A,Buderus S,Greer ML,Dias JA,Veereman-Wauters G,Lionetti P,Sladek M,Martin de Carpi J,Staiano A,Ruemmele FM,Wilson DC,European Society of Pediatric Gast.ESPGHAN revised porto criteria for the diagnosis of inflammatory bowel disease in children and adolescents. Journal of Pediatric Gastroenterology and Nutrition . 2014 被引量：3
  • 7Karin R. Engelhardt,Neil Shah,Intan Faizura-Yeop,Dilara F. Kocacik Uygun,Natalie Frede,Aleixo M. Muise,Eyal Shteyer,Serkan Filiz,Ronnie Chee,Mamoun Elawad,Britta Hartmann,Peter D. Arkwright,Christopher Dvorak,Christoph Klein,Jennifer M. Puck,Bodo Grimbacher,Erik-Oliver Glocker.??Clinical outcome in IL-10– and IL-10 receptor–deficient patients with or without hematopoietic stem cell transplantation(J)The Journal of Allergy and Clinical Immunology . 2012 被引量：1
  • 8Franke A,Mc Govern DP,Barrett JC,Wang K,Radford-Smith GL,Ahmad T,Lees CW,Balschun T,Lee J,Roberts R,Anderson CA,Bis JC,Bumpstead S,Ellinghaus D,Festen EM,Georges M,Green T,Haritunians T,Jostins L,Latiano A,Mathew CG,Montgomery GW,Prescott NJ,Raychaudhuri.Genomewide meta-analysis increases to 71 the number of confirmed Crohn’’s disease susceptibility loci. Nature Genetics . 2010 被引量：2
  • 9Mao H,Yang W,Lee PP,Ho MH,Yang J,Zeng S,Chong CY,Lee TL,Tu W,Lau YL.Exome sequencing identifies novel compound heterozygous mutations of IL-10 receptor 1 in neonatalonset Crohn’’s disease. Genes and Immunity . 2012 被引量：1
  • 10Levine Arie,Griffiths Anne,Markowitz James,Wilson David C,Turner Dan,Russell Richard K,Fell John,Ruemmele Frank M,Walters Thomas,Sherlock Mary,Dubinsky Marla,Hyams Jeffrey S.Pediatric modification of the Montreal classification for inflammatory bowel disease: the Paris classification. Inflammatory Bowel Diseases . 2011 被引量：2

共引文献258

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二级引证文献18

中华儿科杂志
2019年 第7期

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