摘要
无论是在实验室还是工业生产中,通过胺的选择性氧化制备亚胺类化合物都具有重要的意义.秉承原子经济性、环境友好的理念,以蝴蝶型络合物Cu2(ophen)2为催化剂,实现了需氧型的胺的选择性氧化.值得注意的是,该催化体系对醇与胺的氧化交叉偶联、一级胺的氧化偶联和二级胺的氧化脱氢反应都是有效的.反应产率高达93%,亚胺的选择性高达99%.在反应体系中,避免了昂贵的氮氧自由基类化合物的使用,使得该体系更具有潜在的实际应用价值.
The selective catalytic oxidation of amines for the synthesis of imines is important both in laboratory and industrial production.From atom-efficient,economic and environmental view of points,dioxygen selective oxidation of amines was achieved by using wings-opened butterfly-like complex Cu2(ophen)2 as catalyst.It was worth noting that the catalytic system was efficient to the cross-coupling of alcohols with amines,homocoupling of primary amines and oxidative dehydrogenation of secondary amines.The yield is up to 93%and the selectivity of imines is as high as 99%.Avoiding the use of expensive nitroxyl derivatives and base was suitable for practical application.
作者
张玲娟
党宇娇
张献明
Zhang Lingjuan;Dang Yujiao;Zhang Xianming(Key Laboratory of Magnetic Molecules & Magnetic Information Materials,Ministry of Education,School of Chemical and Material Science,Shanxi Normal University,Linfen 041004)
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2019年第6期1650-1654,共5页
Chinese Journal of Organic Chemistry
基金
Project supported by the National Natural Science Foundation of China(No.21402112)
the 1331 Project of Shanxi Province~~
