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无症状颈动脉狭窄与患者轻度认知障碍的相关性研究 被引量:2

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摘要 目的研究无症状的颈动脉狭窄与患者轻度认知障碍是否存在关系。方法选取2016-2017年间就诊于我院神经内科住院部和门诊的80例受试者,根据颈动脉多普勒超声结果评价是否存在颈动脉中度以上狭窄(狭窄程度≥30%)将受试者分为两组,狭窄组和对照组。记录所有受试基本人口学信息、临床资料;使用MoCA,MMSE量表评价认知功能;运用SPSS软件分析相关数据。结果颈动脉狭窄组和对照组患者均经过条件控制在受教育程度、抑郁、智力、吸烟史、心血管危险因素方面不存在差异。组间高血压、高脂血症发病率狭窄组高于对照组(P<0.05)。各组之间MMSE得分无显著区别(P=0.616),MoCA评分狭窄组明显高于对照组(P<0.001)。在MoCA分项评分中,两组视觉空间执行能力、延迟记忆力、注意力方面,对照组高于狭窄组(P<0.05)。且使用MMSE认知评价量表对轻度认知障碍检出率为0.775(31/40)低于MOCA量表的0.775(31/40),差异具有统计学意义(P<0.001,K=0.982)。通过二元Logistic回归分析显示高血脂、高血压、颈动脉狭窄是轻度认知障碍的独立影响因素。结论无症状颈动脉狭窄与轻度认知障碍紧密相连,高血压、高血脂同样也是无症状颈动脉狭窄患者轻度认知障碍的危险因素。在评价轻度认知功能方面,使用MoCA量表可能是更好的选择。
出处 《解放军预防医学杂志》 CAS 2019年第6期169-170,172,共3页 Journal of Preventive Medicine of Chinese People's Liberation Army
基金 河北省科技厅重点研发计划项目(No.jx16277c100D) 保定市科技支撑计划项目(No.17EF253)
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