摘要
目的探究急性心肌梗死并发房颤患者由胺碘酮联合丹参酮ⅡA磺酸钠进行治疗的效果。方法对在医院进行治疗的126例急性心肌梗死合并房颤患者进行分组治疗(依据随机分组法,每组63例)。仅使用盐酸胺碘酮注射液治疗对照组患者,而观察组基于对照组再加用丹参酮ⅡA磺酸钠注射液进行治疗。对比其治疗效果。结果两组患者的CRP水平在治疗前比较,P>0.05,差异无统计学意义;而经过治疗7d和24d后,两组患者的的CRP水平均出现了降低,但观察组下降的更加明显,两组相比,P<0.05,差异有统计学意义;而在心力衰竭发生率、病死率、房颤复发率和不良反应发生率方面,观察组显著较对照组低,两组相比,P<0.05,差异有统计学意义;而在房颤治疗有效率方面,观察组显著高于对照组,两组相比,P<0.05,差异有统计学意义。结论急性心肌梗死合并房颤患者经胺碘酮和丹参酮ⅡA磺酸钠联合治疗效果卓越,可大大降低病死率和不良反应率。
Objective To investigate the effect of amiodarone combined with sodium tanshinone IIA sulfonate in patients with acute myocardial infarction complicated with atrial fibrillation. Methods A total of 126 patients with acute myocardial infarction complicated with atrial fibrillation treated in the hospital were treated with group therapy (according to randomization, 63 patients in each group). The control group was treated only with amiodarone hydrochloride injection, while the observation group was treated with sodium tanshinone Ⅱ A sulfonate injection based on the control group. Compare the therapeutic effects. Results The CRP levels of the two groups were not significantly different before treatment, P > 0.05, the difference was not statistically significant. After 7 d and 24 d, the CRP levels of the two groups decreased, but the decline of the observation group was more obvious. Compared with the difference, P < 0.05, the difference was statistically significant;in the incidence of heart failure, mortality, atrial fibrillation recurrence rate and adverse reaction rate, the observation group was significantly lower than the control group, compared with the two groups, P < 0.05, the difference was statistically significant, In the treatment efficiency of atrial fibrillation, the observation group was significantly higher than the control group, P < 0.05, the difference was statistically significant. Conclusion Patients with acute myocardial infarction complicated with atrial fibrillation have excellent effects in combination with amiodarone and sodium tanshinone IIA sulfonate, which can greatly reduce the mortality and adverse reaction rate.
作者
曹士奎
狄小凯
CAO Shikui;DI Xiaokai(Department of Cardiology,Xuecheng DistrictPeople's Hospital,Shandong Zaozhuang 277000,China)
出处
《中国继续医学教育》
2019年第19期112-114,共3页
China Continuing Medical Education
关键词
胺碘酮
丹参酮ⅡA磺酸钠
急性心肌梗死
房颤
CRP水平
治疗效果
amiodarone
sodium tanshinone IIA sulfonate
acute myocardial infarction
atrial fibrillation
CRP level
therapeutic effect
