摘要
目的采用超声波辅助提取响应面分析优选朱砂根中岩白菜素的提取工艺。方法以岩白菜素提取率为考察指标,在单因素实验基础上选择因素和水平,进行Box-Behnken响应面实验设计,得到最佳操作条件及二次方程响应面模型。结果朱砂根中岩白菜素的最佳提取工艺条件为:超声时间为40min,超声功率为100W,料液比为1∶77。结论Box-Behnken响应面法能优化朱砂根中岩白菜素的提取工艺。
Objective To optimize the extraction technology of bergenin from Radix Ardisiae crenatae by response surface method.Methods Based on the choice of factors and levels according to the results of single factor test,Box-Behnken response surface experiment was designed with the extraction rate of bergenin as the index to obtain the optimal operation conditions and two equations of the response surface model.Results The optimal extraction conditions of bergenin in Radix Ardisiae crenatae were as follows:the ultrasonic time was 40 min,the ultrasonic power was 100 W and the solid to liquid ratio was 1∶77.Conclusion Box-Behnken response surface method can be used to optimize the extraction of bergenin from Radix Ardisiae crenatae.
作者
户宪珍
杨长花
杨文娟
王飞娟
HU Xianzhen;YANG Changhua;YANG Wenjuan;WANG Feijuan(No.215 Hospital of Shaanxi Nuclear Industry,Xianyang 712000,China;Shaanxi Institute of International Trade & Commerce,Xianyang 712046,China;Shaanxi University of Science & Technology,Xi′an 710021,China)
出处
《西北药学杂志》
CAS
2019年第4期458-462,共5页
Northwest Pharmaceutical Journal
基金
陕西省科技厅项目(编号:2016SF-389)
中药绿色制造技术协同创新中心(编号:陕教[2018]12号)
生物医药创新制药技术研究院士专家工作站(编号:陕科协发[2017]事企字15号)
陕西省中药制药关键性技术重点研究室(编号:陕中医药发[2016]29号)
关键词
朱砂根
岩白菜素
提取工艺
响应面法
Radix Ardisiae crenatae
bergenin
extraction process
response surface method
