摘要
微流控技术的商业化是其目前的主要研究内容之一。基于印制电路板(Printed circuit board,PCB)的微流控(Lab-on-PCB)工艺能够结合PCB工艺和发展成熟的聚合物微流控制造技术,构建低成本、标准化和批量化的制造平台,有效推进了微流控技术的商业化。本文针对近20年Lab-on-PCB的研究,通过对芯片典型结构的分析,重点从结构、材料和制作工艺等方面对Lab-on-PCB的研究进展进行综述,总结目前Lab-on-PCB的应用和商业化发展情况,并对该技术的不足、待解决的问题和未来发展方向进行了评述和展望。
Commercialization is the current major theme of microfluidics. Since lab-on-printed circuit board (lab-on-PCB) can integrate PCB technology and polymer microfluidic manufacturing process, a low-cost, standardized and mass productive platform has been formed to promote commercialization efficiently. In this paper, we summarized the research of lab-on-PCB in the past 20 years and reviewed the progress from structures, materials and fabrication methods according to the analysis of typical lab-on-PCB architectures. Besides, the current applications and commercialization, the shortcomings and problems to be solved, and future directions were also discussed and prospected.
作者
常永嘉
尤晖
CHANG Yong-Jia;YOU Hui(Institute of Intelligent Machines, Chinese Academy of Sciences, Hefei 230031, China;University of Science and Technology of China, Hefei 230026, China;School of Mechanical Engineering, Guangxi University, Nanning 530004, China)
出处
《分析化学》
SCIE
EI
CAS
CSCD
北大核心
2019年第7期965-975,共11页
Chinese Journal of Analytical Chemistry
基金
中科院先导专项(No.XDA08040109)资助~~
关键词
印制电路板
微流控芯片
微全分析系统
评述
Printed circuit board
Microfluidics chip
Micrototal analysis system
Review