摘要
目的:探讨诱发电位检查在视神经脊髓炎谱系疾病(NMOSD)中的特征及其与多发性硬化(MS)的鉴别诊断价值。方法:选取15例NMOSD患者作为观察组及14例MS患者作为对照组,记录两组的临床特征,并完善视觉诱发电位(VEP)、脑干听觉诱发电位(BAEP).短潜伏期躯体感觉诱发电位(SLSEP)、三叉神经体感诱发电位(TSEP)检查。结果:与MS组比较,NMOSD组的VEP更多地表现为P100波缺失(P<0.05),而MS组主要表现为P100波潜伏期延长(P<0. 05);MS组BAEP的潜伏期延长者多于NMOSD组(P<0. 05);SLSEP及TSEP的异常表现在两组中无明显差异。结论:VEP及BAEP在NMOSD及MS中具有鉴别诊断价值,SLSEP及TSEP在两种疾病中无明显鉴别诊断价值。
Objective: To investigate the features of evoked potentials in neuromyelitis optica spectrum disorders ( NMOSD) and its differential diagnostic value between NMOSD and multiple sclerosis (MS). Methods: 15 patients with NMOSD as the observation group and 14 patients with MS as the control group were selected to record the clinical characteristics and underwent the examination of visual evoked potentials (VEP), brainstem auditory evoked potentials (BAEP), short latency somatosensory evoked potentials (SLSEP) and trigeminal somatosensory evoked potentials (TSEP). Results: The VEP of NOMSD group showed more absence of P100 (P<0. 05), while MS group showed mainly extension of P100 latency(P<0. 05). The cases with extended latency of BAEP in MS group were more than those in NMOSD group (P<0. 05). There was no significant difference in the abnormal performance of SLSEP and TSEP between the two groups. Conclusion: VEP and BAEP have differen tial diagnostic value in NMOSD and MS. while SLSEP and TSEP have no significant differential diagnosis value in two diseases.
作者
刘丹丹
李淮玉
冯颖
喻廉
LIU Dandan;LI Huaiyu;FENG Ying(Department of Neurology, Anhui Prouincial IIos pital Affiliated to Anhui Med ical UniuersityHefei (230001), Anhui, China)
出处
《癫痫与神经电生理学杂志》
2019年第3期144-147,共4页
Journal of Epileptology and Electroneurophysiology(China)
