摘要
目的研究老年SchatzkerⅡ型胫骨平台骨折术后,开始抗骨质疏松治疗的时机与膝关节功能恢复的关系。方法前瞻性分析2017年1月至2018年1月在甘肃省人民医院接受手术治疗的单侧胫骨平台SchatzkerⅡ型骨折的老年患者。按照开始口服阿仑膦酸钠抗骨质疏松的时机,分为术后1周内、术后3个月后2组,比较2组患者在停用阿仑膦酸钠3个月后的膝创伤与关节炎评分(KOOS)。结果共纳入研究对象33例,术后1周内、术后3个月后开始口服阿仑膦酸钠的分别为19例、14例患者。2组患者停用阿仑膦酸钠3个月后,测得KOOS总分的中位值分别为87(82,89)分、63(56,66)分,Mann-Whitney U检验P<0.05,差异具有统计学意义。结论老年SchatzkerⅡ型胫骨平台骨折术后,术后1周内开始口服阿仑膦酸钠的膝关节功能恢复,优于术后3个月后开始口服。
Objective To study the relationship between the timing of anti-osteoporosis treatment and knee function recovery after surgery for elderly Schatzker typeⅡtibial plateau fractures.Methods Prospective analysis of the elderly patients with Schatzker typeⅡfractures of the unilateral tibial plateau who underwent surgery in Gansu Provincial People’s Hospital from January 2017 to January 2018.According to the timing of oral administration of alendronate against osteoporosis,it was divided into one week after operation group and three months after operation group.Comparison of knee injury and osteoarthritis outcome score(KOOS)in two groups after discontinuation of alendronate for three months were taken.Results A total of 33 patients were enrolled in the study.Nineteen patients received oral alendronate within one week after surgery and 14 patients started oral alendronate three months after surgery.The median of KOOS overall scores in the two groups were 87(82,89),63(56,66),respectively,and Mann-Whitney U test P<0.05 indicating that the difference of knee function recovery was statistically significant.Conclusion In the elderly Schatzker typeⅡtibial plateau fracture,the knee joint function recovered after oral administration of alendronate for within one week postoperative is better than that of three months after surgery.
作者
王展
宋玉鑫
钱耀文
Wang Zhan;Song Yuxin;Qian Yaowen(Gansu Provincial People’s Hospital,Lanhzhou 730000,China)
出处
《中华关节外科杂志（电子版）》
CAS
CSCD
2019年第2期242-244,247,共4页
Chinese Journal of Joint Surgery(Electronic Edition)
关键词
胫骨骨折
关节内骨折
骨质疏松性骨折
药物疗法
老年人
Tibial fractures
Intra-articular fractures
Osteoporotic fractures
Drug therapy
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