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硫酸镁治疗喘憋性肺炎的临床研究

Clinical research on magnesium sulfate in treatment of asthmatic suffocating pneumonia
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摘要 目的探讨小儿喘憋性肺炎行硫酸镁治疗的临床效果。方法选取2016年7月~2018年6月我院儿科收治的喘憋性肺炎患儿共60例,根据患儿入院时间先后顺序进行分组各30例。对照组患儿执行常规对症治疗,观察组患儿在常规治疗基础上行硫酸镁治疗,对两组患者临床症状控制时间、住院时间、血气指标以及临床疗效进行统计分析。结果(1)观察组患儿临床症状控制效果显著优于对照组,观察组患儿喘息缓解时间、咳嗽消失时间、发热消退时间、哮鸣音消失时间均显著少于对照组,观察组患儿整体住院时间相较于对照组显著更少,组间数据差异有统计学意义(P <0.05);(2)观察组血气指标控制效果显著优于对照组,观察患儿氧分压及血氧饱和度相较于对照组显著更高,二氧化碳分压则显著更低,组间数据差异有统计学意义(P <0.05);(3)观察组患儿临床总有效率为90.00%,对照组患儿临床总有效率为66.67%,前者优于后者,组间数据差异有统计学意义(P <0.05)。结论小儿喘憋性肺炎临床治疗中给药硫酸镁可有效缓解其临床症状,纠正其异常的血气指标,进而提升其临床疗效,因此该种治疗方案值得在临床中普及应用。 Objective To explore the clinical curative effects of magnesium sulfate in treatment of asthmatic suffocating pneumonia. Methods 60 children with asthmatic suffocating pneumonia who were admitted and treated in department of pediatrics in our hospital from July 2016 to June 2018 were selected. According to the order of admission, they were divided into two groups, with 30 cases in each group. Children in the control group were given routine symptomatic treatment while children in the observation group were given conventional treatment with magnesium sulfate. The clinical symptoms control time, hospital stay, blood gas index and clinical curative effects were statistically calculated and analyzed. Results ① The control effect of clinical symptoms of the observation group was significantly better than that of the control group, which was reflected in that the time of wheezing relief, cough disappearance, fever resolution and asthma disappearance of the observation group were significantly less than those of the control group. The overall hospital stay in the observation group was significantly shorter than that in the control group. Differences in data between two groups were statistically significant(P < 0.05).② The control effect of blood gas index of the observation group was significantly better than that of the control group, which was reflected in that the oxygen partial pressure and blood oxygen saturation of children of the observation group were significantly higher and the carbon dioxide partial pressure of the observation group was significantly lower than that of the control group. Differences in data between two groups were statistically significant(P < 0.05).③ The clinical effective rate was 90.00% in the observation group and 66.67% in the control group, and the former was better than the latter. Differences in data between two groups were statistically significant(P < 0.05). Conclusion In clinical treatment of children with asthmatic suffocating pneumonia, magnesium sulfate can effectively all
作者 江少青 蔡晓华 刘志伟 JIANG Shaoqing;CAI Xiaohua;LIU Zhiwei(Puning People’s Hospital, Guangdong, Jieyang 515300, China)
出处 《中国医药科学》 2019年第11期217-219,共3页 China Medicine And Pharmacy
关键词 硫酸镁 喘憋性肺炎 小儿患者 血气指标 Magnesium sulfate Asthmatic suffocating pneumonia Children Blood gas index
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