摘要
目的:探究高级别宫颈上皮内瘤变的临床诊断及治疗体会。方法:回顾性分析111例高级别宫颈上皮内瘤变(cervical intraepithelial neoplasia,CIN)患者行液基薄层细胞学(thin-layer cytology test,TCT)检查结果,并与术后病理学检查结果进行比较,治疗方式包括宫颈冷刀锥切除术(cold knife conization,CKC)与子宫全切术,观察患者治疗效果。结果:TCT检出高级别CIN共103例,检出率为92.8 %,与手术病理学检查结果比较差异无统计学意义( P >0.05);71例行CKC治疗,随访0.5年3例复发;40例行子宫全切术,随访0.5年1例复发;两种手术方式术后复发率比较差异无统计学意义( P >0.05)。结论:TCT诊断CIN具有较高准确率,可作为筛查CIN的首选;CKC及子宫全切治疗高级别宫颈上皮内瘤病变均具有较好的疗效,可结合患者实际情况选择相应的手术方式。
Objective: To explore the clinical diagnosis and treatment of high-grade cervical intraepithelial neoplasia. Methods:By retrospective analyzing111 patients with high-grade cervical intraepithelial neoplasia (CIN) received liquid-based thin-layer cytology test (TCT). The results were compared with those of pathological examination. Treatment methods include cervical cold knife conization (CKC) and total hysterectomy. The therapeutic effect of the patients was followed up. Results:There were103 cases of high grade CIN detected by TCT and the detection rate was 92.8 %. There was no significant difference between TCT and pathological examination ( P >0.05). Of the111 patients, 71 were treated with CKC, 3 cases recurred after half a year of follow-up,40 were treated with total hysterectomy, and 1case recurred after half a year of follow-up. There was no significant difference in the recurrence rate between the two methods ( P >0.05). Conclusion:TCT has high accuracy in diagnosing CIN, and can be used as the first choice for screening CIN. CKC and total hysterectomy for high-grade CIN have a good effect and can be combined with the actual situation of patients to choose the appropriate surgical methods.
作者
徐方方
XU Fangfang(First People's Hospital of Nanyang, Nanyang 473000,China)
出处
《包头医学院学报》
CAS
2019年第4期71-72,共2页
Journal of Baotou Medical College
关键词
宫颈上皮内瘤变
宫颈冷刀锥切除术
子宫全切术
Cervical intraepithelial neoplasia
Cervical cold knifeconization
Total hysterectomy
