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microRNAs在慢性肾脏病肾脏纤维化中作用的研究进展 被引量:5

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摘要 微小核糖核酸(microRNAs,miRNAs)是一种内源性、高度保守的非编码小RNA,主要参与生物体内转录后水平基因表达的调控,从而在各种疾病的发病机制中起重要作用。近年研究表明,在肾脏组织中存在的一些miRNAs对肾脏纤维化的发生与发展有着重要的作用。作者就miRNAs在慢性肾脏病(CKD)肾脏纤维化中促进作用、抑制作用及矛盾作用的研究进展进行综述。
出处 《现代医学》 2019年第4期478-482,共5页 Modern Medical Journal
基金 国家自然科学基金资助项目(81560122)
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