摘要
目的:观察不同剂型利多卡因局部外用治疗碘造影剂渗出的效果。方法:将80例CT检查过程中造影剂渗出的患者采用区组随机法分为A组(使用50%硫酸镁溶液)、B组(使用2%利多卡因溶液)、C组(使用2%利多卡因胶浆)、D组(使用5%复方利多卡因乳膏) 4组外用药物治疗,每组20例。观察4组治疗有效率、显效率、起效时间及治愈时间。结果:A、B、C、D组有效率依次为85%、90%、90%、95%,显效率依次为15%、45%、50%、60%,起效时间依次为(7. 5±2. 5)、(6. 0±2. 1)、(4. 7±1. 8)、(3. 6±1. 5) h,治愈时间依次为(36. 5±5. 4)、(32. 6±4. 2)、(29. 2±3. 8)、(23. 6±4. 3) h;4组有效率差异无统计学意义(P> 0. 05),B、C、D组显效率均高于A组(P <0. 05),A、B、C、D组起效时间、治愈时间依次递减(P <0. 05)。结论:相比50%硫酸镁溶液及2%利多卡因溶液,5%复方利多卡因乳膏、2%利多卡因胶浆外用治疗碘造影剂渗出具有起效快、使用便利的优势,值得进一步研究及推广使用。
Objective: To observe the effect of lidocaine in different dosage forms on the treatment of iodine contrast exudation. Methods: Eighty cases of patients with exudation of contrast agent during CT examination were divided into group A( 50% magnesium sulfate solution),group B( 2% lidocaine solution),group C( 2% lidocaine glue) and group D( 5% compound lidocaine cream) according to the random-block method with 20 cases in each group. The total effective rate,markedly effective rate,initiation time of drug and healing time were observed in the four groups. Results: The total effective rate was 85%,90%,90% and 95%,the markedly effective rate was15%,45%,50% and 60%,the initiation time of drug was( 7. 5 ± 2. 5),( 6. 0 ± 2. 1),( 4. 7 ± 1. 8),( 3. 6 ± 1. 5)h and the healing time was( 36. 5 ± 5. 4),( 32. 6 ± 4. 2),( 29. 2 ± 3. 8),( 23. 6 ± 4. 3) h in group A,B,C and D respectively. There was no statistically significant difference of the total effective rate between the four groups( P >0. 05). Markedly effective rate in three groups with lidocaine was higher than that in group with magnesium sulfate( P < 0. 05). Conclusion: Compared with 50% magnesium sulfate solution and 2% lidocaine solution,5%compound lidocaine cream and 2% lidocaine glue have the advantages of quick response,convenient to use for external treatment of iodine contrast exudation,which is worth further studying and promoting.
作者
宋朝晖
李惠平
许小蓉
乔丽珍
SONG Zhaohui;LI Huiping;XU X iaorong;QIAO Lizhen(Department of Supply Room,Liuzhou People's Hospital, Liuzhou 545006, China;Outpatient Department,Liuzhou People's Hospital, Liuzhou 545006, China;Department of Radiology,Liuzhou People's Hospital, Liuzhou 545006, China)
出处
《现代医学》
2019年第4期411-414,共4页
Modern Medical Journal
基金
广西壮族自治区卫生和计划生育委员会自筹经费科研项目(Z2015130)
柳州市科学研究与技术开发计划项目(2016G020209)
关键词
碘造影剂
渗出
利多卡因
不同剂型
iodine contrast agent
exudation
lidocaine
different dosage forms
