摘要
目的对比多奈哌齐、银杏叶治疗老年痴呆的临床疗效。方法选取我院2017年6月-2018年11月收治的老年痴呆患者74例为研究对象,随机分为银杏叶组与多奈哌齐组,对比2组疗效及不良反应发生情况。结果多奈哌齐组的治疗有效率显著优于银杏叶组,不良反应的发生率显著低于银杏叶组(P<0.05)。治疗后2组患者的MMSE、词汇记忆与Blessed痴呆量表的评分显示,多奈哌齐组显著优于银杏叶组(P<0.05)。结论多奈哌齐治疗老年痴呆患者的效果明显,副作用小,可作为首选用药于临床上推广。
Objective To explore the difference of efficacy between donepezil and ginkgo biloba in the treatment of Alzheimer. Methods From June 2017 to November 2018,74 cases of Alzheimer patients were selected and randomly divided into ginkgo biloba group and donepezil group for two months of treatment. During this period,the occurrence of adverse reactions was observed and recorded. After treatment,the efficacy of the two groups of patients was analyzed. In addition,the patients were rated with MMSE,verbal memory and the Blessed dementia scale before and after treatment. Results The effective rate of donepezil group was significantly better than that of ginkgo biloba group,and the incidence of adverse reactions was significantly lower than that of ginkgo biloba group(P<0.05).The scores of MMSE,verbal memory and Blessed dementia scale after treatment showed that donepezil group were significantly better than ginkgo biloba group. Conclusion When donepezil is used to treat patients with Alzheimer’s disease,the effect is obvious and the side effects are small. Therefore,donepezil should be recommended for the treatment of Alzheimer.
作者
王蕾
Wang Lei(The People's Hospital of Pengzhou City,pengzhou,Sichuan 611930)
出处
《基层医学论坛》
2019年第20期2819-2820,共2页
The Medical Forum
关键词
老年痴呆
多奈哌齐
银杏叶
疗效
不良反应
Senile dementia
Donepezil
Ginkgo biloba
Curative effect
Adverse reaction
