摘要
目的探讨肝癌破裂出血非手术治疗患者预后评价的方法。方法回顾性分析69例肝癌破裂出血非手术治疗患者的一般资料、检查、检验结果和生存时间,将不同的危险因素进行积分赋值,依据积分的高低将患者分为高危组和低危组,采用Kaplan-Meier方法对比两种患者生存时间的差异。作为对比,同时采用多因素Cox回归和单因素Kaplan-Meier方法相结合的方法,探讨影响患者预后的因素。结果无论采用经肝动脉插管栓塞或化疗栓塞(TAE/TACE),还是保守治疗,危险因素积分的方法均能将患者进一步分为高危组和低危组,两者生存时间的差异具有统计学意义(P<0.05)。而生存时间相关多因素及单因素分析相结合的方法所得的影响因素并不适合作为独立判断患者预后的指标。结论采用危险因素积分的方法有助于判断肝癌破裂出血非手术治疗患者的预后。
Objective To explore the method for the prognostic evaluation of patients with rupture and bleeding of liver cancer treated by non-surgical way.Methods Retrospectively we analyzed the general data,examination,test results and survival time of 69 patients with rupture and bleeding of liver cancer treated by non-surgical way.Different risk factors were assigned to a specified score.According to the sum of scores,the patients were divided into high-risk group and low-risk group.Kaplan-Meier method was used to compare the difference in survival time between the two patients.As a comparison,a combination of multivariate Cox regression method and univariate Kaplan-Meier method was used to explore the factors affecting the prognosis of patients.Results By transarterial chemoembolization/transarterial embolization(TAE/TACE)or conservative treatment,the method of risk factor scores further divided the patients into high-risk group and low-risk group.The difference in survival time between the two groups was statistically significant(P<0.05).However,influence factors made by the method of combining multi-factor and univariate-factor analysis were not suitable as independent indicators for the judgment of patient prognosis.Conclusion The method of risk factor scores is helpful to evaluate the prognosis of patients with rupture and bleeding of liver cancer treated in non-surgical way.
作者
陈智贤
于新发
王璟
CHEN Zhixian;YU Xinfa;WANG Jing(Shunde Hospital of Southern Medical University,Foshan,China)
出处
《现代医院》
2019年第5期726-728,731,共4页
Modern Hospitals
基金
佛山市科技局医学类科技攻关项目(2016AB003543)
关键词
肝癌
肝癌破裂
治疗
预后
Liver Cancer
Rupture and Bleeding of Liver Cancer
Treatment
Prognosis
