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PCT和D-二聚体联合检测在脓毒症患者中的变化特点

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摘要 目的观察降钙素原(PCT)和D-二聚体(D-D)联合检测在脓毒症患者中的变化特点。方法选取医院收治的152例脓毒症患者作为观察组,根据脓毒症严重程度,将其分为脓毒症亚组(76例)、重度脓毒症亚组(51例)及脓毒症休克亚组(25例);另根据随访结果,将其分为病死亚组(55例)、存活亚组(97例);选取同期于本院健康体检者50例作为对照组,检测各组PCT和D-D水平。结果观察组PCT及D-D水平均较对照组高(P <0. 01);脓毒症休克亚组PCT及D-D水平>重度脓毒症亚组>脓毒症亚组(P <0. 01); 28 d内,152例脓毒症患者总病死率为36. 18%(55/152),其中脓毒症亚组8例,重度脓毒症亚组31例,脓毒症休克亚组16例;病死亚组患者PCT及D-D水平较存活亚组高(P <0. 01)。结论脓毒症患者采取PCT和D-D联合检测具有较高的应用价值,其在脓毒症早期诊断、病情判断及预后评估中均发挥重要作用。
作者 王世立
出处 《临床合理用药杂志》 2019年第14期128-129,共2页 Chinese Journal of Clinical Rational Drug Use
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