摘要
目的观察比较右美托咪定与丙泊酚用于全麻患者后苏醒质量和安全性。方法选取医院行全麻手术患者110例为研究对象,随机分为A、B组,每组55例。2组均接受全身麻醉,A组术中给予右美托咪定,B组术中给予丙泊酚,比较2组术后睁眼时间与拔管时间,苏醒期躁动程度、Rammsay镇静评分,以及不良反应发生率。结果2组术后睁眼时间比较差异无统计学意义(P> 0. 05); A组拔管时间短于B组(P <0. 01); A组苏醒期躁动评分与Rammsay镇静评分优于B组(P <0. 01); A组不良反应发生率较为5. 45%,低于B组的29. 09%(P <0. 01)。结论右美托咪定用于全麻患者术后可缩短术后拔管时间,也能减轻苏醒期躁动程度,减少不良反应,值得推广应用。
Objective To observe and compare the recovery quality and safety of dexmedetomidine and propofol after general anesthesia. Methods 110 patients undergoing general anesthesia were randomly divided into group A and group B with 55 cases in each group. Both groups received general anesthesia,dexmedetomidine was given in group A and propofol was given in group B. The open eye time and extubation time,restlessness during recovery period,Rammsay sedation score and incidence of adverse reactions were compared between the two groups. Results There was no significant difference in the opening time between the two groups ( P > 0. 05). The extubation time of group A was shorter than that of group B ( P < 0. 01). The restlessness score and Rammsay sedation score in group A were better than those in group B ( P < 0. 01). The incidence of adverse reactions in group A was 5. 45%,lower than that in group B ( 29. 09%,P < 0. 01). Conclusion Dexmedetomidine can shorten the extubation time after general anesthesia,reduce the restlessness during recovery and reduce adverse reactions,which is worthy of popularization and application.
作者
张莉容
ZHANG Li-rong(Hejiang County Hospital of Traditional Chinese Medicine, Sichuan 646200, China)
出处
《临床合理用药杂志》
2019年第14期14-15,共2页
Chinese Journal of Clinical Rational Drug Use
关键词
右美托咪定
丙泊酚
全麻
苏醒质量
安全性
Dexmedetomidine
Propofol
General anesthesia
Awakening quality
Safety
