摘要
目的:观察养血止痛丸治疗踝关节骨折术后患者的临床疗效,并对患者的关节功能、骨代谢等相关指标进行分析。方法:选取2015年12月至2017年12月洛阳正骨医院收治的接受手术治疗的旋前外旋型踝关节骨折患者110例作为研究对象,随机分为对照组与观察组,每组55例。对照组患者在术后以踝关节功能康复训练,观察组加予口服养血止痛丸进行治疗。分别在治疗前、治疗后记录患者的踝关节量表(Olerud-Molander、AOFAS)评分、关节功能、血清Ca、ALP、BGP、PICP、Total-PINP、β-CTX水平等指标进行比较分析。结果:在治疗后,2组患者的踝关节Olerud-Molander及AOFAS评分评分都较治疗前明显提高(P<0.05);患者踝关节背伸、跖屈时的肌力和ROM均较治疗前改善(P<0.05),血清Ca、ALP、BGP、PICP水平较治疗前有明显提高(P<0.05),而Total-PINP、β-CTX水平则明显降低(P<0.05),观察组均明显优于对照组(P<0.05),且观察组的不良情况发生率为9.09%,对照组的不良情况发生率为16.36%,观察组明显优于对照组(P<0.05)。结论:养血止痛丸可以有效的改善踝关节骨折术后患者的临床症状,踝关节活动及肌力明显好转,这可能与养血止痛丸其发挥养血舒筋,改善骨代谢,促进骨折损伤的修复的作用有关。
Objective: To observe the clinical efficacy of Yangxue Zhitong Pills in the treatment of patients after ankle fracture operation,and to analyze the related indexes of joint function and bone metabolism. Methods: A total of 110 patients with pronated external rotation ankle fracture admitted to Luoyang Zhenggu Hospital from December 2015 to December 2017 were selected as subjects according to random number table method.The patients were randomly divided into an observation group and a control group,with 55 cases in each group.The patients in the control group were performed with ankle joint function rehabilitation training after operation,and the observation group was treated with oral administration of Yangxue Zhitong Pills.The patients′ ankle joint scale (Olerud-Molander,AOFAS) score,joint function,serum Ca,ALP,BGP,PICP,Total-PINP and β-CTX levels were recorded before and after treatment for comparative analysis. Results: After treatment,the Olerud-Molander and AOFAS scores of the ankle joint in both groups were significantly increased than those before treatment ( P <0.05);the muscle strength and ROM of the ankle joint flexion and plantar flexion were better than before treatment ( P <0.05),and the serum Ca,ALP,BGP,PICP levels were significantly increased than before treatment ( P <0.05);the levels of Total-PINP and β-CTX were significantly decreased ( P <0.05).The observation group was significantly better than the control group ( P <0.05).The rate of adverse events in the observation group was 9.09%,and the rate of adverse events was 16.36%.The observation group was significantly better than the control group ( P <0.05). Conclusion: Yangxue Zhitong Pills can effectively improve the clinical symptoms of patients with ankle fracture after operation,and the ankle activity and muscle strength are obviously improved.This may be related to Yangxue Zhitong Pills′ role of nourishing blood and relieving muscles,improving bone metabolism and promoting the repair of fracture injury.
作者
刘晓东
崔利萍
李朝晖
侯立功
Liu Xiaodong;Cui Liping;Li Zhaohui;Hou Ligong(Luoyang Zhenggu Hospital of Henan Province/Henan Provincial Orthopedic Hospital Foot and Ankle Surgery,Zhengzhou 450000,China;Zhengzhou University Children′s Hospital Outpatient Department,Zhengzhou 450000,China;Henan International Joint Laboratory for Pediatric Diseases Prevention and Control of Zhengzhou University Children′s Hospital,Zhengzhou 450000,China)
出处
《世界中医药》
CAS
2019年第5期1237-1241,共5页
World Chinese Medicine
基金
2015年度河南省医学科技攻关计划项目(201503236)
