摘要
目的:探讨认知心理治疗对首发精神分裂症患者的疗效。方法:选取首发精神分裂症患者113例,随机分为研究组( n =59)和对照组( n =54)。两组在单一用药治疗2周后,研究组采用认知心理治疗+药物治疗,对照组采用一般心理健康宣教+药物治疗,疗程8 周。于治疗后2周、10周及6个月后采用阳性与阴性症状量表(PANSS)、世界卫生组织生存质量测定量表简表(WHOQOL-BREF)、治疗态度问卷(ITAQ)及康复状态量表(MRSS)量表评估精神症状及社会功能。结果:(1)治疗 10周后,两组PANSS总分、一般病理因子分比较,差异有统计学意义( P <0.05),治疗6个月后,两组间PANSS总分、阳性因子分、阴性因子分、一般病理因子分比较,差异均有统计学意义(均 P <0.05);(2)在治疗10周后,研究组MRSS D 分值、MRSS C 分值低于对照组( P <0.05),在治疗6个月后,MRSS D 、MRSS A 、MRSS C 、MRSS B 分值低于对照组( P <0.01);(3)治疗10周及6个月后,两组间ITAQ评分差异有统计学意义( P <0.05);(4)在治疗10周后,研究组心理领域评分和总分高于对照组( P <0.05);在治疗6个月后,研究组在社会关系和心理领域维评分及总评分高于对照组( P <0.01)。结论:认知心理治疗可提升首发精神分裂症患者的疗效、治疗依从性、康复状态及心理健康水平,值得临床推广应用。
Objective: To investigate the efficacy of cognitive psychotherapy for first-episode schizophrenia patients. Methods: A total of 113 patients with first-episode schizophrenia were divided into a study group ( n =59)and a control group ( n =54).After two weeks of drug treatment,the patients in the study group received cognitive psychotherapy combined with drug therapy,and those in the control group received conventional mental health education combined with drug therapy.The Positive and Negative Symptom Scale (PANSS) score,World Health Organization Quality of Life-brief (WHOQOL-BREF) score,Therapeutic Attitude Questionnaire (ITAQ) score,and Morningside Rehabilitation Status Scale (MRSS) score were compared. Results:(1) After 10 weeks of treatment,the PANSS total score and general pathological factor score were significantly different between the two groups ( P <0.05).After 6 months of treatment,there were significant differences in PANSS total score,positive factor score,negative factor score and general pathological factor score between the two groups ( P <0.05).(2) After 10 weeks of treatment,the scores of MRSS D and MRSS C in the study group were lower than those in the control group ( P <0.05),and the scores of MRSS D ,MRSS A ,MRSS C and MRSS B in the study group were lower than those in the control group at 6 months after treatment ( P <0.01).(3) After 10 weeks and 6 months of treatment,there was a significant difference in ITAQ score between the two groups ( P <0.05).(4) After 10 weeks of treatment,the scores of psychological field and total score in the study group were higher than those in the control group ( P <0.05).After 6 months of treatment,the scores of social and psychological dimension and total scores in the study group were higher than those in the control group ( P <0.01). Conclusion: Cognitive psychotherapy could improve the efficacy,treatment compliance,rehabilitation status and mental health of patients with first-episode schizophrenia.
作者
卢国强
李辉
李英英
沈全荣
闫妍
汪晓晖
易正辉
Lu Guoqiang;Li Hui;Li Yingying;Shen Quanrong;Yan Yan;Wang Xiaohui;Yi Zhenghui(Mental Health Center,Qingpu District,Shanghai 201700,China;Shanghai Mental Health Center,Shanghai 201700,China)
出处
《广西医科大学学报》
CAS
2019年第5期771-775,共5页
Journal of Guangxi Medical University
基金
国家自然科学基金资助项目(No.81671326)
上海市青浦区科学技术发展基金资助项目(No.2016-16)
关键词
认知心理治疗
精神分裂症
疗效
康复
cognitive psychotherapy
schizophrenia
curative effect
rehabilitation
