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四环素类药物治疗牙周炎的作用机制及临床应用进展 被引量:3

Mechanism and Clinical Application of Tetracycline Drugs in the Treatment of Periodontitis
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摘要 牙周炎是临床上较为常见口腔疾病之一,具有极高的发病率,通常是由微生物(特异性)所引起的龈下感染,典型临床表现在于牙槽骨吸收与牙周组织炎症。以往临床上选择采用传统机械疗法进行治疗,主要是彻底清除牙周局部刺激物,但是治疗效果令人不满意,仅能够祛除附着于牙周的菌斑,对于非附着性菌斑而言不具备治疗作用,因此临床上在寻找新的辅助治疗方法,以达到改善临床症状的目的,对提高患者的生活质量具有积极作用。本文为了研究四环素类药物治疗牙周炎的作用机制及临床应用效果,将近年来国内外相关四环素类药物治疗牙周炎等文献资料进行展开性综述,从而为更多的临床工作人员提供有效参考依据。 Periodontitis is one of the most common oral diseases in clinic. It has a very high incidence and usually is subgingival infection caused by microorganism (specific). The typical clinical manifestation are alveolar bone resorption and periodontal inflammation. In the past, traditional mechanical therapy was used in clinical treatment, mainly to completely remove periodontal local irritants, but the treatment effect was not satisfactory, only the plaque attached to the periodontal can be removed, for non attachable plaque it has no therapeutic effect. Therefore, in clinical practice, it is necessary to find new adjuvant treatment methods to improve clinical symptoms and improve the quality of life of patients. In order to study the mechanism and clinical application of tetracycline drugs in the treatment of periodontitis, this paper has carried out an extensive review of relevant literatures on tetracycline drugs in the treatment of periodontitis at home and abroad in recent years, so as to provide more clinical staff with effective reference.
作者 杨文华 Yang Wenhua(Department of Stomatology, Tianjin Beichen Hospital, Tianjin 300400)
出处 《数理医药学杂志》 2019年第6期884-885,共2页 Journal of Mathematical Medicine
关键词 四环素类药物 牙周炎 作用机制 临床应用效果 tetracycline drugs periodontitis mechanism of action clinical application effect
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